Lu H - Search Results

1

Novel complex crystal structure of prolyl hydroxylase domain-containing protein 2 (PHD2): 2,8-Diazaspiro[4.5]decan-1-ones as potent, orally bioavailable PHD2 inhibitors.

Deng G, Zhao B, Ma Y, Xu Q, Wang H, Yang L, Zhang Q, Guo TB, Zhang W, Jiao Y, Cai X, Zhang J, Liu H, Guan X, Lu H, Xiang J, Elliott JD, Lin X, Ren F. Deng G, et al. Among authors: lu h. Bioorg Med Chem. 2013 Nov 1;21(21):6349-58. doi: 10.1016/j.bmc.2013.08.046. Epub 2013 Sep 3. Bioorg Med Chem. 2013. PMID: 24055079

2

Crucial role of interleukin-7 in T helper type 17 survival and expansion in autoimmune disease.

Liu X, Leung S, Wang C, Tan Z, Wang J, Guo TB, Fang L, Zhao Y, Wan B, Qin X, Lu L, Li R, Pan H, Song M, Liu A, Hong J, Lu H, Zhang JZ. Liu X, et al. Among authors: lu h, lu l. Nat Med. 2010 Feb;16(2):191-7. doi: 10.1038/nm.2077. Epub 2010 Jan 10. Nat Med. 2010. Retraction in: Nat Med. 2013 Dec;19(12):1673. doi: 10.1038/nm1213-1673 PMID: 20062065 Retracted.

3

Discovery of thiadiazole amides as potent, S1P₃-sparing agonists of sphingosine-1-phosphate 1 (S1P₁) receptor.

Xu H, Zhang H, Luan L, Xu Y, Li C, Wang Y, Han F, Yang T, Ren F, Xiang JN, Elliott JD, Zhao Y, Guo TB, Lu H, Zhang W, Hirst D, Lindon M, Lin X. Xu H, et al. Among authors: lu h. Bioorg Med Chem Lett. 2012 Apr 1;22(7):2456-9. doi: 10.1016/j.bmcl.2012.02.016. Epub 2012 Feb 15. Bioorg Med Chem Lett. 2012. PMID: 22386243

4

Indole-propionic acid derivatives as potent, S1P3-sparing and EAE efficacious sphingosine-1-phosphate 1 (S1P1) receptor agonists.

Meng Q, Zhao B, Xu Q, Xu X, Deng G, Li C, Luan L, Ren F, Wang H, Xu H, Xu Y, Zhang H, Xiang JN, Elliott JD, Guo TB, Zhao Y, Zhang W, Lu H, Lin X. Meng Q, et al. Among authors: lu h. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2794-7. doi: 10.1016/j.bmcl.2012.02.083. Epub 2012 Mar 3. Bioorg Med Chem Lett. 2012. PMID: 22429468

5

Discovery of novel 1,2,4-thiadiazole derivatives as potent, orally active agonists of sphingosine 1-phosphate receptor subtype 1 (S1P(1)).

Ren F, Deng G, Wang H, Luan L, Meng Q, Xu Q, Xu H, Xu X, Zhang H, Zhao B, Li C, Guo TB, Yang J, Zhang W, Zhao Y, Jia Q, Lu H, Xiang JN, Elliott JD, Lin X. Ren F, et al. Among authors: lu h. J Med Chem. 2012 May 10;55(9):4286-96. doi: 10.1021/jm2016107. Epub 2012 Apr 20. J Med Chem. 2012. PMID: 22500954

6

Identification of benzoxazole analogs as novel, S1P(3) sparing S1P(1) agonists.

Deng G, Meng Q, Liu Q, Xu X, Xu Q, Ren F, Guo TB, Lu H, Xiang JN, Elliott JD, Lin X. Deng G, et al. Among authors: lu h. Bioorg Med Chem Lett. 2012 Jun 15;22(12):3973-7. doi: 10.1016/j.bmcl.2012.04.095. Epub 2012 Apr 28. Bioorg Med Chem Lett. 2012. PMID: 22583616

7

Promoting remyelination for the treatment of multiple sclerosis: opportunities and challenges.

Zhang Y, Guo TB, Lu H. Zhang Y, et al. Among authors: lu h. Neurosci Bull. 2013 Apr;29(2):144-54. doi: 10.1007/s12264-013-1317-z. Epub 2013 Apr 5. Neurosci Bull. 2013. PMID: 23558587 Free PMC article. Review.

8

A pan-allelic human SIRPα-blocking antibody, ES004-B5, promotes tumor killing by enhancing macrophage phagocytosis and subsequently inducing an effective T-cell response.

Niu X, Wang C, Jiang H, Gao R, Lu Y, Guo X, Zhou H, Cui X, Sun J, Qiu Q, Sun D, Lu H. Niu X, et al. Among authors: lu y, lu h. Antib Ther. 2024 Aug 28;7(3):266-280. doi: 10.1093/abt/tbae022. eCollection 2024 Jul. Antib Ther. 2024. PMID: 39257438 Free PMC article.

9

Nose to Brain: Exploring the Progress of Intranasal Delivery of Solid Lipid Nanoparticles and Nanostructured Lipid Carriers.

Zheng Y, Cui L, Lu H, Liu Z, Zhai Z, Wang H, Shao L, Lu Z, Song X, Zhang Y. Zheng Y, et al. Among authors: lu h. Int J Nanomedicine. 2024 Nov 21;19:12343-12368. doi: 10.2147/IJN.S497480. eCollection 2024. Int J Nanomedicine. 2024. PMID: 39606563 Free PMC article. Review.

10

Multi-targeted olink proteomics analyses of cerebrospinal fluid from patients with aneurysmal subarachnoid hemorrhage.

Ding R, Wu L, Wei S, Lu H, Qin X, Liu X, Wang Y, Liu W, Li H, Luo B, Xie T, Chen Z. Ding R, et al. Among authors: lu h. Proteome Sci. 2024 Nov 27;22(1):11. doi: 10.1186/s12953-024-00236-x. Proteome Sci. 2024. PMID: 39604965

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