Wu F - Search Results

1

Novel small-molecule AMPK activator orally exerts beneficial effects on diabetic db/db mice.

Li YY, Yu LF, Zhang LN, Qiu BY, Su MB, Wu F, Chen DK, Pang T, Gu M, Zhang W, Ma WP, Jiang HW, Li JY, Nan FJ, Li J. Li YY, et al. Among authors: wu f. Toxicol Appl Pharmacol. 2013 Dec 1;273(2):325-34. doi: 10.1016/j.taap.2013.09.006. Epub 2013 Sep 18. Toxicol Appl Pharmacol. 2013. PMID: 24055643

2

Design, synthesis, and biological evaluation of isoquinoline-1,3,4-trione derivatives as potent caspase-3 inhibitors.

Chen YH, Zhang YH, Zhang HJ, Liu DZ, Gu M, Li JY, Wu F, Zhu XZ, Li J, Nan FJ. Chen YH, et al. Among authors: wu f. J Med Chem. 2006 Mar 9;49(5):1613-23. doi: 10.1021/jm050896o. J Med Chem. 2006. PMID: 16509578

3

Isoquinoline-1,3,4-trione and its derivatives attenuate beta-amyloid-induced apoptosis of neuronal cells.

Zhang YH, Zhang HJ, Wu F, Chen YH, Ma XQ, Du JQ, Zhou ZL, Li JY, Nan FJ, Li J. Zhang YH, et al. Among authors: wu f. FEBS J. 2006 Nov;273(21):4842-52. doi: 10.1111/j.1742-4658.2006.05483.x. Epub 2006 Oct 9. FEBS J. 2006. PMID: 17032354 Free article.

4

Novel irreversible caspase-1 inhibitor attenuates the maturation of intracellular interleukin-1beta.

Ma XQ, Zhang HJ, Zhang YH, Chen YH, Wu F, Du JQ, Yu HP, Zhou ZL, Li JY, Nan FJ, Li J. Ma XQ, et al. Among authors: wu f. Biochem Cell Biol. 2007 Feb;85(1):56-65. doi: 10.1139/o06-149. Biochem Cell Biol. 2007. PMID: 17464345

5

Isoquinoline-1,3,4-trione derivatives inactivate caspase-3 by generation of reactive oxygen species.

Du JQ, Wu J, Zhang HJ, Zhang YH, Qiu BY, Wu F, Chen YH, Li JY, Nan FJ, Ding JP, Li J. Du JQ, et al. Among authors: wu f, wu j. J Biol Chem. 2008 Oct 31;283(44):30205-15. doi: 10.1074/jbc.M803347200. Epub 2008 Sep 2. J Biol Chem. 2008. PMID: 18768468 Free PMC article.

6

High-throughput assay for modulators of mitochondrial membrane potential identifies a novel compound with beneficial effects on db/db mice.

Qiu BY, Turner N, Li YY, Gu M, Huang MW, Wu F, Pang T, Nan FJ, Ye JM, Li JY, Li J. Qiu BY, et al. Among authors: wu f. Diabetes. 2010 Jan;59(1):256-65. doi: 10.2337/db09-0223. Epub 2009 Oct 15. Diabetes. 2010. PMID: 19833880 Free PMC article.

7

8,8-Dimethyldihydroberberine with improved bioavailability and oral efficacy on obese and diabetic mouse models.

Cheng Z, Chen AF, Wu F, Sheng L, Zhang HK, Gu M, Li YY, Zhang LN, Hu LH, Li JY, Li J. Cheng Z, et al. Among authors: wu f. Bioorg Med Chem. 2010 Aug 15;18(16):5915-24. doi: 10.1016/j.bmc.2010.06.085. Epub 2010 Jul 1. Bioorg Med Chem. 2010. PMID: 20663675

8

Novel small-molecule PGC-1α transcriptional regulator with beneficial effects on diabetic db/db mice.

Zhang LN, Zhou HY, Fu YY, Li YY, Wu F, Gu M, Wu LY, Xia CM, Dong TC, Li JY, Shen JK, Li J. Zhang LN, et al. Among authors: wu f, wu ly. Diabetes. 2013 Apr;62(4):1297-307. doi: 10.2337/db12-0703. Epub 2012 Dec 18. Diabetes. 2013. PMID: 23250358 Free PMC article.

9

Discovery of a Bioactive Inhibitor with a New Scaffold for Cystathionine γ-Lyase.

Hu Y, Wang L, Han X, Zhou Y, Zhang T, Wang L, Hong T, Zhang W, Guo XX, Sun J, Qi Y, Yu J, Liu H, Wu F. Hu Y, et al. Among authors: wu f. J Med Chem. 2019 Feb 14;62(3):1677-1683. doi: 10.1021/acs.jmedchem.8b01720. Epub 2018 Dec 31. J Med Chem. 2019. PMID: 30562026

10

Novel inhibitors of human DOPA decarboxylase extracted from Euonymus glabra Roxb.

Ren J, Zhang Y, Jin H, Yu J, Zhou Y, Wu F, Zhang W. Ren J, et al. Among authors: wu f. ACS Chem Biol. 2014 Apr 18;9(4):897-903. doi: 10.1021/cb500009r. Epub 2014 Feb 10. ACS Chem Biol. 2014. PMID: 24471650

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