Elevated blood Hsp60, its structural similarities and cross-reactivity with thyroid molecules, and its presence on the plasma membrane of oncocytes point to the chaperonin as an immunopathogenic factor in Hashimoto's thyroiditis.
Marino Gammazza A, Rizzo M, Citarrella R, Rappa F, Campanella C, Bucchieri F, Patti A, Nikolic D, Cabibi D, Amico G, Conaldi PG, San Biagio PL, Montalto G, Farina F, Zummo G, Conway de Macario E, Macario AJ, Cappello F.
Marino Gammazza A, et al. Among authors: montalto g.
Cell Stress Chaperones. 2014 May;19(3):343-53. doi: 10.1007/s12192-013-0460-9. Epub 2013 Sep 22.
Cell Stress Chaperones. 2014.
PMID: 24057177
Free PMC article.