Parrotta L - Search Results

1

Identification of new natural DNA G-quadruplex binders selected by a structure-based virtual screening approach.

Artese A, Costa G, Ortuso F, Parrotta L, Alcaro S. Artese A, et al. Among authors: parrotta l. Molecules. 2013 Sep 30;18(10):12051-70. doi: 10.3390/molecules181012051. Molecules. 2013. PMID: 24084014 Free PMC article.

2

Rational design, synthesis, biophysical and antiproliferative evaluation of fluorenone derivatives with DNA G-quadruplex binding properties.

Alcaro S, Artese A, Iley JN, Missailidis S, Ortuso F, Parrotta L, Pasceri R, Paduano F, Sissi C, Trapasso F, Vigorita MG. Alcaro S, et al. Among authors: parrotta l. ChemMedChem. 2010 Apr 6;5(4):575-83. doi: 10.1002/cmdc.200900541. ChemMedChem. 2010. PMID: 20135671

3

Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders.

Alcaro S, Artese A, Costa G, Distinto S, Ortuso F, Parrotta L. Alcaro S, et al. Among authors: parrotta l. Biochimie. 2011 Aug;93(8):1267-74. doi: 10.1016/j.biochi.2011.06.014. Epub 2011 Jun 16. Biochimie. 2011. PMID: 21699954

4

The polymorphisms of DNA G-quadruplex investigated by docking experiments with telomestatin enantiomers.

Alcaro S, Costa G, Distinto S, Moraca F, Ortuso F, Parrotta L, Artese A. Alcaro S, et al. Among authors: parrotta l. Curr Pharm Des. 2012;18(14):1873-9. doi: 10.2174/138161212799958495. Curr Pharm Des. 2012. PMID: 22376115

5

Identification and characterization of new DNA G-quadruplex binders selected by a combination of ligand and structure-based virtual screening approaches.

Alcaro S, Musetti C, Distinto S, Casatti M, Zagotto G, Artese A, Parrotta L, Moraca F, Costa G, Ortuso F, Maccioni E, Sissi C. Alcaro S, et al. Among authors: parrotta l. J Med Chem. 2013 Feb 14;56(3):843-55. doi: 10.1021/jm3013486. Epub 2013 Jan 22. J Med Chem. 2013. PMID: 23294188

6

Toward the design of new DNA G-quadruplex ligands through rational analysis of polymorphism and binding data.

Artese A, Costa G, Distinto S, Moraca F, Ortuso F, Parrotta L, Alcaro S. Artese A, et al. Among authors: parrotta l. Eur J Med Chem. 2013 Oct;68:139-49. doi: 10.1016/j.ejmech.2013.07.022. Epub 2013 Aug 11. Eur J Med Chem. 2013. PMID: 23974014

7

Structure-based virtual screening of novel natural alkaloid derivatives as potential binders of h-telo and c-myc DNA G-quadruplex conformations.

Rocca R, Moraca F, Costa G, Alcaro S, Distinto S, Maccioni E, Ortuso F, Artese A, Parrotta L. Rocca R, et al. Among authors: parrotta l. Molecules. 2014 Dec 24;20(1):206-23. doi: 10.3390/molecules20010206. Molecules. 2014. PMID: 25547724 Free PMC article.

8

Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement.

Rocca R, Costa G, Artese A, Parrotta L, Ortuso F, Maccioni E, Pinato O, Greco ML, Sissi C, Alcaro S, Distinto S, Moraca F. Rocca R, et al. Among authors: parrotta l. ChemMedChem. 2016 Aug 19;11(16):1721-33. doi: 10.1002/cmdc.201600053. Epub 2016 Mar 23. ChemMedChem. 2016. PMID: 27008476

9

Molecular and structural aspects of clinically relevant mutations related to the approved non-nucleoside inhibitors of HIV-1 reverse transcriptase.

Alcaro S, Alteri C, Artese A, Ceccherini-Silberstein F, Costa G, Ortuso F, Parrotta L, Perno CF, Svicher V. Alcaro S, et al. Among authors: parrotta l. Drug Resist Updat. 2011 Jun;14(3):141-9. doi: 10.1016/j.drup.2011.01.002. Epub 2011 Feb 3. Drug Resist Updat. 2011. PMID: 21295512 Review.

10

Docking analysis and resistance evaluation of clinically relevant mutations associated with the HIV-1 non-nucleoside reverse transcriptase inhibitors nevirapine, efavirenz and etravirine.

Alcaro S, Alteri C, Artese A, Ceccherini-Silberstein F, Costa G, Ortuso F, Bertoli A, Forbici F, Santoro MM, Parrotta L, Flandre P, Masquelier B, Descamps D, Calvez V, Marcelin AG, Perno CF, Sing T, Svicher V. Alcaro S, et al. Among authors: parrotta l. ChemMedChem. 2011 Dec 9;6(12):2203-13. doi: 10.1002/cmdc.201100362. Epub 2011 Sep 27. ChemMedChem. 2011. PMID: 21953939

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