Bach T - Search Results

1

Amythiamicin D and related thiopeptides as inhibitors of the bacterial elongation factor EF-Tu: modification of the amino acid at carbon atom C2 of ring C dramatically influences activity.

Gross S, Nguyen F, Bierschenk M, Sohmen D, Menzel T, Antes I, Wilson DN, Bach T. Gross S, et al. Among authors: bach t. ChemMedChem. 2013 Dec;8(12):1954-62. doi: 10.1002/cmdc.201300323. Epub 2013 Sep 17. ChemMedChem. 2013. PMID: 24106106

2

Total syntheses of the thiopeptides amythiamicin C and D.

Ammer C, Bach T. Ammer C, et al. Among authors: bach t. Chemistry. 2010 Dec 17;16(47):14083-93. doi: 10.1002/chem.201002144. Chemistry. 2010. PMID: 20960446

3

Synthesis of the heterocyclic core of the GE 2270 antibiotics and structure elucidation of a major degradation product.

Heckmann G, Bach T. Heckmann G, et al. Among authors: bach t. Angew Chem Int Ed Engl. 2005 Feb 11;44(8):1199-201. doi: 10.1002/anie.200461715. Angew Chem Int Ed Engl. 2005. PMID: 15651011 No abstract available.

4

Synthesis and configurational assignment of the amino alcohol in the eastern fragment of the GE2270 antibiotics by regio- and stereoselective addition of 2-metalated 4-bromothiazoles to alpha-chiral electrophiles.

Delgado O, Heckmann G, Müller HM, Bach T. Delgado O, et al. Among authors: bach t. J Org Chem. 2006 Jun 9;71(12):4599-608. doi: 10.1021/jo060462g. J Org Chem. 2006. PMID: 16749794

5

Total synthesis of the thiazolyl peptide GE2270 A.

Müller HM, Delgado O, Bach T. Müller HM, et al. Among authors: bach t. Angew Chem Int Ed Engl. 2007;46(25):4771-4. doi: 10.1002/anie.200700684. Angew Chem Int Ed Engl. 2007. PMID: 17503407 No abstract available.

6

Stereoselective preparation of (E)-configured 1,2-disubstituted propenes from two aldehydes by a two-carbon stitching strategy: convergent synthesis of 18,21-diisopropyl-geldanamycin hydroquinone and its C7 epimer.

Hampel T, Neubauer T, van Leeuwen T, Bach T. Hampel T, et al. Among authors: bach t. Chemistry. 2012 Aug 13;18(33):10382-92. doi: 10.1002/chem.201201600. Epub 2012 Jul 16. Chemistry. 2012. PMID: 22807045

7

Total synthesis of (+)-wailupemycin B.

Kirsch S, Bach T. Kirsch S, et al. Among authors: bach t. Angew Chem Int Ed Engl. 2003 Oct 6;42(38):4685-7. doi: 10.1002/anie.200351455. Angew Chem Int Ed Engl. 2003. PMID: 14533164 No abstract available.

8

Conformationally constrained beta-amino acid derivatives by intramolecular [2 + 2]-photocycloaddition of a tetronic acid amide and subsequent lactone ring opening.

Basler B, Schuster O, Bach T. Basler B, et al. Among authors: bach t. J Org Chem. 2005 Nov 25;70(24):9798-808. doi: 10.1021/jo0515226. J Org Chem. 2005. PMID: 16292808

9

Synthesis of enantiomerically pure bicyclo[4.2.0]octanes by Cu-catalyzed [2+2] photocycloaddition and enantiotopos-differentiating ring opening.

Braun I, Rudroff F, Mihovilovic MD, Bach T. Braun I, et al. Among authors: bach t. Angew Chem Int Ed Engl. 2006 Aug 18;45(33):5541-3. doi: 10.1002/anie.200600946. Angew Chem Int Ed Engl. 2006. PMID: 16850509 No abstract available.

10

Concise total synthesis of the thiazolyl peptide antibiotic GE2270 A.

Delgado O, Müller HM, Bach T. Delgado O, et al. Among authors: bach t. Chemistry. 2008;14(8):2322-39. doi: 10.1002/chem.200701823. Chemistry. 2008. PMID: 18270986

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