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COVID-19 progression and convalescence in common variable immunodeficiency patients show dysregulated adaptive immune responses and persistent type I interferon and inflammasome activation.
Rodríguez-Ubreva J, Calafell-Segura J, Calvillo CL, Keller B, Ciudad L, Handfield LF, de la Calle-Fabregat C, Godoy-Tena G, Andrés-León E, Hoo R, Porter T, Prigmore E, Hofmann M, Decker A, Martín J, Vento-Tormo R, Warnatz K, Ballestar E. Rodríguez-Ubreva J, et al. Among authors: hofmann m. Nat Commun. 2024 Nov 28;15(1):10344. doi: 10.1038/s41467-024-54732-x. Nat Commun. 2024. PMID: 39609471
Impaired SARS-CoV-2-Specific CD8+ T Cells After Infection or Vaccination but Robust Hybrid T Cell Immunity in Patients with Multiple Myeloma.
Shoumariyeh K, Csernalabics B, Salimi Alizei E, Reinscheid M, Giese S, Ciminski K, Kochs G, Schwemmle M, Lang-Meli J, Maas M, Roehlen N, Karl V, Graeser A, Sogukpinar O, von Metzler I, Grathwohl D, Rasche L, Hebart H, Kull M, Emmerich F, Waller CF, Duyster J, Engelhardt M, Hartmann TN, Bengsch B, Boettler T, Neumann-Haefelin C, Hofmann M, Thimme R, Luxenburger H. Shoumariyeh K, et al. Among authors: hofmann m. Vaccines (Basel). 2024 Nov 1;12(11):1249. doi: 10.3390/vaccines12111249. Vaccines (Basel). 2024. PMID: 39591152 Free PMC article.
Concurrent SOS1 and MEK suppression inhibits signaling and growth of NF1-null melanoma.
Marasco M, Kumar D, Seale T, Borrego SG, Kaplun E, Aricescu I, Cole S, Qeriqi B, Qiu J, Chen X, Bahr A, Fidele D, Hofmann MH, Gerlach D, Savarese F, Merghoub T, Wolchok JD, Yao Z, de Stanchina E, Solit D, Misale S, Rosen N. Marasco M, et al. Among authors: hofmann mh. Cell Rep Med. 2024 Nov 19;5(11):101818. doi: 10.1016/j.xcrm.2024.101818. Epub 2024 Nov 1. Cell Rep Med. 2024. PMID: 39488215 Free article.
PD-1 and LAG-3: synergistic fostering of T cell exhaustion.
Hofmann M, Thimme R, Schamel WW. Hofmann M, et al. Signal Transduct Target Ther. 2024 Oct 18;9(1):291. doi: 10.1038/s41392-024-02000-1. Signal Transduct Target Ther. 2024. PMID: 39424778 Free PMC article. No abstract available.
1,658 results