Loew R - Search Results

1

TCR-engineered T cells: a model of inducible TCR expression to dissect the interrelationship between two TCRs.

Reuß S, Sebestyén Z, Heinz N, Loew R, Baum C, Debets R, Uckert W. Reuß S, et al. Among authors: loew r. Eur J Immunol. 2014 Jan;44(1):265-74. doi: 10.1002/eji.201343591. Epub 2013 Oct 20. Eur J Immunol. 2014. PMID: 24114521 Free PMC article.

2

Improved Tet-responsive promoters with minimized background expression.

Loew R, Heinz N, Hampf M, Bujard H, Gossen M. Loew R, et al. BMC Biotechnol. 2010 Nov 24;10:81. doi: 10.1186/1472-6750-10-81. BMC Biotechnol. 2010. PMID: 21106052 Free PMC article.

3

Graded or threshold response of the tet-controlled gene expression: all depends on the concentration of the transactivator.

Heinz N, Hennig K, Loew R. Heinz N, et al. Among authors: loew r. BMC Biotechnol. 2013 Jan 22;13:5. doi: 10.1186/1472-6750-13-5. BMC Biotechnol. 2013. PMID: 23336718 Free PMC article.

4

Retroviral and transposon-based tet-regulated all-in-one vectors with reduced background expression and improved dynamic range.

Heinz N, Schambach A, Galla M, Maetzig T, Baum C, Loew R, Schiedlmeier B. Heinz N, et al. Among authors: loew r. Hum Gene Ther. 2011 Feb;22(2):166-76. doi: 10.1089/hum.2010.099. Epub 2010 Dec 19. Hum Gene Ther. 2011. PMID: 20825282

5

Tumor rejection by local interferon gamma induction in established tumors is associated with blood vessel destruction and necrosis.

Briesemeister D, Sommermeyer D, Loddenkemper C, Loew R, Uckert W, Blankenstein T, Kammertoens T. Briesemeister D, et al. Among authors: loew r. Int J Cancer. 2011 Jan 15;128(2):371-8. doi: 10.1002/ijc.25350. Epub 2010 Mar 23. Int J Cancer. 2011. PMID: 20333679

6

HEK293-based production platform for γ-retroviral (self-inactivating) vectors: application for safe and efficient transfer of COL7A1 cDNA.

Hennig K, Raasch L, Kolbe C, Weidner S, Leisegang M, Uckert W, Titeux M, Hovnanian A, Kuehlcke K, Loew R. Hennig K, et al. Among authors: loew r. Hum Gene Ther Clin Dev. 2014 Dec;25(4):218-28. doi: 10.1089/humc.2014.083. Hum Gene Ther Clin Dev. 2014. PMID: 25381930

7

Simplified generation of high-titer retrovirus producer cells for clinically relevant retroviral vectors by reversible inclusion of a lox-P-flanked marker gene.

Loew R, Selevsek N, Fehse B, von Laer D, Baum C, Fauser A, Kuehlcke K. Loew R, et al. Mol Ther. 2004 May;9(5):738-46. doi: 10.1016/j.ymthe.2004.02.010. Mol Ther. 2004. PMID: 15120335 Free article.

8

Improving transcriptional termination of self-inactivating gamma-retroviral and lentiviral vectors.

Schambach A, Galla M, Maetzig T, Loew R, Baum C. Schambach A, et al. Among authors: loew r. Mol Ther. 2007 Jun;15(6):1167-73. doi: 10.1038/sj.mt.6300152. Epub 2007 Apr 3. Mol Ther. 2007. PMID: 17406345 Free article.

9

Overcoming promoter competition in packaging cells improves production of self-inactivating retroviral vectors.

Schambach A, Mueller D, Galla M, Verstegen MM, Wagemaker G, Loew R, Baum C, Bohne J. Schambach A, et al. Among authors: loew r. Gene Ther. 2006 Nov;13(21):1524-33. doi: 10.1038/sj.gt.3302807. Epub 2006 Jun 8. Gene Ther. 2006. PMID: 16763662

10

Mechanisms controlling titer and expression of bidirectional lentiviral and gammaretroviral vectors.

Maetzig T, Galla M, Brugman MH, Loew R, Baum C, Schambach A. Maetzig T, et al. Among authors: loew r. Gene Ther. 2010 Mar;17(3):400-11. doi: 10.1038/gt.2009.129. Epub 2009 Oct 22. Gene Ther. 2010. PMID: 19847204

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