Lewis AR - Search Results

1

Dectin-2 sensing of house dust mite is critical for the initiation of airway inflammation.

Clarke DL, Davis NH, Campion CL, Foster ML, Heasman SC, Lewis AR, Anderson IK, Corkill DJ, Sleeman MA, May RD, Robinson MJ. Clarke DL, et al. Among authors: lewis ar. Mucosal Immunol. 2014 May;7(3):558-67. doi: 10.1038/mi.2013.74. Epub 2013 Oct 16. Mucosal Immunol. 2014. PMID: 24129160 Free PMC article.

2

Development of a mouse model mimicking key aspects of a viral asthma exacerbation.

Clarke DL, Davis NH, Majithiya JB, Piper SC, Lewis A, Sleeman MA, Corkill DJ, May RD. Clarke DL, et al. Clin Sci (Lond). 2014 Apr;126(8):567-80. doi: 10.1042/CS20130149. Clin Sci (Lond). 2014. PMID: 24152048

3

Preclinical characterisation of the GM-CSF receptor as a therapeutic target in rheumatoid arthritis.

Greven DE, Cohen ES, Gerlag DM, Campbell J, Woods J, Davis N, van Nieuwenhuijze A, Lewis A, Heasmen S, McCourt M, Corkill D, Dodd A, Elvin J, Statache G, Wicks IP, Anderson IK, Nash A, Sleeman MA, Tak PP. Greven DE, et al. Ann Rheum Dis. 2015 Oct;74(10):1924-30. doi: 10.1136/annrheumdis-2014-205234. Epub 2014 Jun 16. Ann Rheum Dis. 2015. PMID: 24936585 Free PMC article.

4

Inhibition of mast cells: a novel mechanism by which nintedanib may elicit anti-fibrotic effects.

Overed-Sayer C, Miranda E, Dunmore R, Liarte Marin E, Beloki L, Rassl D, Parfrey H, Carruthers A, Chahboub A, Koch S, Güler-Gane G, Kuziora M, Lewis A, Murray L, May R, Clarke D. Overed-Sayer C, et al. Thorax. 2020 Sep;75(9):754-763. doi: 10.1136/thoraxjnl-2019-214000. Epub 2020 Jul 24. Thorax. 2020. PMID: 32709610 Free PMC article.

5

Transformation of the tumour microenvironment by a CD40 agonist antibody correlates with improved responses to PD-L1 blockade in a mouse orthotopic pancreatic tumour model.

Luheshi NM, Coates-Ulrichsen J, Harper J, Mullins S, Sulikowski MG, Martin P, Brown L, Lewis A, Davies G, Morrow M, Wilkinson RW. Luheshi NM, et al. Oncotarget. 2016 Apr 5;7(14):18508-20. doi: 10.18632/oncotarget.7610. Oncotarget. 2016. PMID: 26918344 Free PMC article.

6

Divergent roles for Clusterin in Lung Injury and Repair.

Habiel DM, Camelo A, Espindola M, Burwell T, Hanna R, Miranda E, Carruthers A, Bell M, Coelho AL, Liu H, Pilataxi F, Clarke L, Grant E, Lewis A, Moore B, Knight DA, Hogaboam CM, Murray LA. Habiel DM, et al. Sci Rep. 2017 Nov 13;7(1):15444. doi: 10.1038/s41598-017-15670-5. Sci Rep. 2017. PMID: 29133960 Free PMC article.

7

Optimization of RNA extraction from laser captured microdissected glomeruli from formalin-fixed paraffin-embedded mouse kidney samples for Nanostring analysis.

Hay A, Lapointe JM, Lewis A, Moreno Quinn C, Miranda E. Hay A, et al. Histol Histopathol. 2020 Jan;35(1):57-68. doi: 10.14670/HH-18-135. Epub 2019 Jun 11. Histol Histopathol. 2020. PMID: 31184368

8

Antibody validation of immunohistochemistry for biomarker discovery: recommendations of a consortium of academic and pharmaceutical based histopathology researchers.

Howat WJ, Lewis A, Jones P, Kampf C, Pontén F, van der Loos CM, Gray N, Womack C, Warford A. Howat WJ, et al. Methods. 2014 Nov;70(1):34-8. doi: 10.1016/j.ymeth.2014.01.018. Epub 2014 Feb 11. Methods. 2014. PMID: 24525140 Free PMC article.

9

MHC class I chain-related protein A and B (MICA and MICB) are predominantly expressed intracellularly in tumour and normal tissue.

Ghadially H, Brown L, Lloyd C, Lewis L, Lewis A, Dillon J, Sainson R, Jovanovic J, Tigue NJ, Bannister D, Bamber L, Valge-Archer V, Wilkinson RW. Ghadially H, et al. Br J Cancer. 2017 Apr 25;116(9):1208-1217. doi: 10.1038/bjc.2017.79. Epub 2017 Mar 23. Br J Cancer. 2017. PMID: 28334733 Free PMC article.

10

Design and Preclinical Evaluation of a Novel B7-H4-Directed Antibody-Drug Conjugate, AZD8205, Alone and in Combination with the PARP1-Selective Inhibitor AZD5305.

Kinneer K, Wortmann P, Cooper ZA, Dickinson NJ, Masterson L, Cailleau T, Hutchinson I, Vijayakrishnan B, McFarlane M, Ball K, Davies M, Lewis A, Huang Y, Rosenbaum AI, Yuan J, Chesebrough J, Anderton J, Monks N, Novick S, Wang J, Dimasi N, Christie RJ, Sabol D, Tosto FA, Wallez Y, Leo E, Albertella MR, Staniszewska AD, Tice DA, Howard PW, Luheshi N, Sapra P. Kinneer K, et al. Clin Cancer Res. 2023 Mar 14;29(6):1086-1101. doi: 10.1158/1078-0432.CCR-22-2630. Clin Cancer Res. 2023. PMID: 36355054

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