Shaughnessy J - Search Results

1

Factor H-dependent alternative pathway inhibition mediated by porin B contributes to virulence of Neisseria meningitidis.

Lewis LA, Vu DM, Vasudhev S, Shaughnessy J, Granoff DM, Ram S. Lewis LA, et al. Among authors: shaughnessy j. mBio. 2013 Oct 15;4(5):e00339-13. doi: 10.1128/mBio.00339-13. mBio. 2013. PMID: 24129254 Free PMC article.

2

Functional comparison of the binding of factor H short consensus repeat 6 (SCR 6) to factor H binding protein from Neisseria meningitidis and the binding of factor H SCR 18 to 20 to Neisseria gonorrhoeae porin.

Shaughnessy J, Lewis LA, Jarva H, Ram S. Shaughnessy J, et al. Infect Immun. 2009 May;77(5):2094-103. doi: 10.1128/IAI.01561-08. Epub 2009 Mar 9. Infect Immun. 2009. PMID: 19273554 Free PMC article.

3

Impaired immunogenicity of a meningococcal factor H-binding protein vaccine engineered to eliminate factor h binding.

Beernink PT, Shaughnessy J, Ram S, Granoff DM. Beernink PT, et al. Among authors: shaughnessy j. Clin Vaccine Immunol. 2010 Jul;17(7):1074-8. doi: 10.1128/CVI.00103-10. Epub 2010 Jun 2. Clin Vaccine Immunol. 2010. PMID: 20519444 Free PMC article.

4

A meningococcal factor H binding protein mutant that eliminates factor H binding enhances protective antibody responses to vaccination.

Beernink PT, Shaughnessy J, Braga EM, Liu Q, Rice PA, Ram S, Granoff DM. Beernink PT, et al. Among authors: shaughnessy j. J Immunol. 2011 Mar 15;186(6):3606-14. doi: 10.4049/jimmunol.1003470. Epub 2011 Feb 16. J Immunol. 2011. PMID: 21325619 Free PMC article.

5

Molecular characterization of the interaction between sialylated Neisseria gonorrhoeae and factor H.

Shaughnessy J, Ram S, Bhattacharjee A, Pedrosa J, Tran C, Horvath G, Monks B, Visintin A, Jokiranta TS, Rice PA. Shaughnessy J, et al. J Biol Chem. 2011 Jun 24;286(25):22235-42. doi: 10.1074/jbc.M111.225516. Epub 2011 Apr 29. J Biol Chem. 2011. PMID: 21531728 Free PMC article.

6

Enhanced bacteremia in human factor H transgenic rats infected by Neisseria meningitidis.

Vu DM, Shaughnessy J, Lewis LA, Ram S, Rice PA, Granoff DM. Vu DM, et al. Among authors: shaughnessy j. Infect Immun. 2012 Feb;80(2):643-50. doi: 10.1128/IAI.05604-11. Epub 2011 Nov 21. Infect Immun. 2012. PMID: 22104107 Free PMC article.

7

The effect of human factor H on immunogenicity of meningococcal native outer membrane vesicle vaccines with over-expressed factor H binding protein.

Beernink PT, Shaughnessy J, Pajon R, Braga EM, Ram S, Granoff DM. Beernink PT, et al. Among authors: shaughnessy j. PLoS Pathog. 2012;8(5):e1002688. doi: 10.1371/journal.ppat.1002688. Epub 2012 May 10. PLoS Pathog. 2012. PMID: 22589720 Free PMC article.

8

Fusion protein comprising factor H domains 6 and 7 and human IgG1 Fc as an antibacterial immunotherapeutic.

Shaughnessy J, Vu DM, Punjabi R, Serra-Pladevall J, DeOliveira RB, Granoff DM, Ram S. Shaughnessy J, et al. Clin Vaccine Immunol. 2014 Oct;21(10):1452-9. doi: 10.1128/CVI.00444-14. Epub 2014 Aug 20. Clin Vaccine Immunol. 2014. PMID: 25143339 Free PMC article.

9

Heterogeneity in rhesus macaque complement factor H binding to meningococcal factor H binding protein (FHbp) informs selection of primates to assess immunogenicity of FHbp-based vaccines.

Beernink PT, Shaughnessy J, Stefek H, Ram S, Granoff DM. Beernink PT, et al. Among authors: shaughnessy j. Clin Vaccine Immunol. 2014 Nov;21(11):1505-11. doi: 10.1128/CVI.00517-14. Epub 2014 Sep 3. Clin Vaccine Immunol. 2014. PMID: 25185576 Free PMC article.

10

Virulence of Group A Streptococci Is Enhanced by Human Complement Inhibitors.

Ermert D, Shaughnessy J, Joeris T, Kaplan J, Pang CJ, Kurt-Jones EA, Rice PA, Ram S, Blom AM. Ermert D, et al. Among authors: shaughnessy j. PLoS Pathog. 2015 Jul 22;11(7):e1005043. doi: 10.1371/journal.ppat.1005043. eCollection 2015 Jul. PLoS Pathog. 2015. PMID: 26200783 Free PMC article.

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