Chowdhury SR - Search Results

1

The lignan glycosides lyoniside and saracoside poison the unusual type IB topoisomerase of Leishmania donovani and kill the parasite both in vitro and in vivo.

Saha S, Mukherjee T, Chowdhury S, Mishra A, Chowdhury SR, Jaisankar P, Mukhopadhyay S, Majumder HK. Saha S, et al. Among authors: chowdhury sr, chowdhury s. Biochem Pharmacol. 2013 Dec 15;86(12):1673-87. doi: 10.1016/j.bcp.2013.10.004. Epub 2013 Oct 14. Biochem Pharmacol. 2013. PMID: 24134912

2

Novel betulin derivatives as antileishmanial agents with mode of action targeting type IB DNA topoisomerase.

Chowdhury S, Mukherjee T, Sengupta S, Chowdhury SR, Mukhopadhyay S, Majumder HK. Chowdhury S, et al. Among authors: chowdhury sr. Mol Pharmacol. 2011 Oct;80(4):694-703. doi: 10.1124/mol.111.072785. Epub 2011 Jul 12. Mol Pharmacol. 2011. PMID: 21750153

3

Disuccinyl betulin triggers metacaspase-dependent endonuclease G-mediated cell death in unicellular protozoan parasite Leishmania donovani.

Chowdhury S, Mukherjee T, Chowdhury SR, Sengupta S, Mukhopadhyay S, Jaisankar P, Majumder HK. Chowdhury S, et al. Among authors: chowdhury sr. Antimicrob Agents Chemother. 2014;58(4):2186-201. doi: 10.1128/AAC.02193-13. Epub 2014 Jan 27. Antimicrob Agents Chemother. 2014. PMID: 24468787 Free PMC article.

4

Isobenzofuranone derivatives exhibit antileishmanial effect by inhibiting type II DNA topoisomerase and inducing host response.

Mishra A, Vinayagam J, Saha S, Chowdhury S, Chowdhury SR, Jaisankar P, Majumder HK. Mishra A, et al. Among authors: chowdhury sr, chowdhury s. Pharmacol Res Perspect. 2014 Dec;2(6):e00070. doi: 10.1002/prp2.70. Epub 2014 Aug 24. Pharmacol Res Perspect. 2014. PMID: 25505614 Free PMC article.

5

A new bisbenzylisoquinoline alkaloid isolated from Thalictrum foliolosum, as a potent inhibitor of DNA topoisomerase IB of Leishmania donovani.

Kumar A, Chowdhury SR, Sarkar T, Chakrabarti T, Majumder HK, Jha T, Mukhopadhyay S. Kumar A, et al. Among authors: chowdhury sr. Fitoterapia. 2016 Mar;109:25-30. doi: 10.1016/j.fitote.2015.11.021. Epub 2015 Nov 26. Fitoterapia. 2016. PMID: 26625837

6

A Novel Spirooxindole Derivative Inhibits the Growth of Leishmania donovani Parasites both In Vitro and In Vivo by Targeting Type IB Topoisomerase.

Saha S, Acharya C, Pal U, Chowdhury SR, Sarkar K, Maiti NC, Jaisankar P, Majumder HK. Saha S, et al. Among authors: chowdhury sr. Antimicrob Agents Chemother. 2016 Sep 23;60(10):6281-93. doi: 10.1128/AAC.00352-16. Print 2016 Oct. Antimicrob Agents Chemother. 2016. PMID: 27503653 Free PMC article.

7

Voacamine alters Leishmania ultrastructure and kills parasite by poisoning unusual bi-subunit topoisomerase IB.

Chowdhury SR, Kumar A, Godinho JLP, De Macedo Silva ST, Zuma AA, Saha S, Kumari N, Rodrigues JCF, Sundar S, Dujardin JC, Roy S, De Souza W, Mukhopadhyay S, Majumder HK. Chowdhury SR, et al. Biochem Pharmacol. 2017 Aug 15;138:19-30. doi: 10.1016/j.bcp.2017.05.002. Epub 2017 May 5. Biochem Pharmacol. 2017. PMID: 28483460

8

DNA Topoisomerases in Unicellular Pathogens: Structure, Function, and Druggability.

Chowdhury SR, Majumder HK. Chowdhury SR, et al. Trends Biochem Sci. 2019 May;44(5):415-432. doi: 10.1016/j.tibs.2018.12.001. Epub 2019 Jan 1. Trends Biochem Sci. 2019. PMID: 30609953 Review.

9

Synthesis and Biological Evaluation of Calothrixins B and their Deoxygenated Analogues.

Muthu Ramalingam B, Dhatchana Moorthy N, Chowdhury SR, Mageshwaran T, Vellaichamy E, Saha S, Ganesan K, Rajesh BN, Iqbal S, Majumder HK, Gunasekaran K, Siva R, Mohanakrishnan AK. Muthu Ramalingam B, et al. Among authors: chowdhury sr. J Med Chem. 2018 Feb 8;61(3):1285-1315. doi: 10.1021/acs.jmedchem.7b01797. Epub 2018 Jan 22. J Med Chem. 2018. PMID: 29313676

10

Isobenzofuranone derivative JVPH3, an inhibitor of L. donovani topoisomerase II, disrupts mitochondrial architecture in trypanosomatid parasites.

Chowdhury SR, Godinho JLP, Vinayagam J, Zuma AA, Silva STM, Jaisankar P, Rodrigues JCF, De Souza W, Majumder HK. Chowdhury SR, et al. Sci Rep. 2018 Aug 9;8(1):11940. doi: 10.1038/s41598-018-30405-w. Sci Rep. 2018. PMID: 30093616 Free PMC article.

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