Jaisankar P - Search Results

1

The lignan glycosides lyoniside and saracoside poison the unusual type IB topoisomerase of Leishmania donovani and kill the parasite both in vitro and in vivo.

Saha S, Mukherjee T, Chowdhury S, Mishra A, Chowdhury SR, Jaisankar P, Mukhopadhyay S, Majumder HK. Saha S, et al. Among authors: jaisankar p. Biochem Pharmacol. 2013 Dec 15;86(12):1673-87. doi: 10.1016/j.bcp.2013.10.004. Epub 2013 Oct 14. Biochem Pharmacol. 2013. PMID: 24134912

2

An insight into the mechanism of inhibition of unusual bi-subunit topoisomerase I from Leishmania donovani by 3,3'-di-indolylmethane, a novel DNA topoisomerase I poison with a strong binding affinity to the enzyme.

Roy A, Das BB, Ganguly A, Bose Dasgupta S, Khalkho NV, Pal C, Dey S, Giri VS, Jaisankar P, Dey S, Majumder HK. Roy A, et al. Among authors: jaisankar p. Biochem J. 2008 Jan 15;409(2):611-22. doi: 10.1042/BJ20071286. Biochem J. 2008. PMID: 17922678

3

Mitochondria-dependent reactive oxygen species-mediated programmed cell death induced by 3,3'-diindolylmethane through inhibition of F0F1-ATP synthase in unicellular protozoan parasite Leishmania donovani.

Roy A, Ganguly A, BoseDasgupta S, Das BB, Pal C, Jaisankar P, Majumder HK. Roy A, et al. Among authors: jaisankar p. Mol Pharmacol. 2008 Nov;74(5):1292-307. doi: 10.1124/mol.108.050161. Epub 2008 Aug 14. Mol Pharmacol. 2008. PMID: 18703668

4

Topoisomerase I gene mutations at F270 in the large subunit and N184 in the small subunit contribute to the resistance mechanism of the unicellular parasite Leishmania donovani towards 3,3'-diindolylmethane.

Roy A, BoseDasgupta S, Ganguly A, Jaisankar P, Majumder HK. Roy A, et al. Among authors: jaisankar p. Antimicrob Agents Chemother. 2009 Jun;53(6):2589-98. doi: 10.1128/AAC.01648-08. Epub 2009 Mar 30. Antimicrob Agents Chemother. 2009. PMID: 19332675 Free PMC article.

5

Assignment of UV-vis spectrum of (3,3')-diindolylmethane, a Leishmania donovani topoisomerase IB inhibitor and a candidate DNA minor groove binder.

Coletta A, Morozzo della Rocca B, Jaisankar P, Majumder HK, Chillemi G, Sanna N, Desideri A. Coletta A, et al. Among authors: jaisankar p. J Phys Chem A. 2010 Jul 8;114(26):7121-6. doi: 10.1021/jp101494d. J Phys Chem A. 2010. PMID: 20550156

6

Involvement of ROS in chlorogenic acid-induced apoptosis of Bcr-Abl+ CML cells.

Rakshit S, Mandal L, Pal BC, Bagchi J, Biswas N, Chaudhuri J, Chowdhury AA, Manna A, Chaudhuri U, Konar A, Mukherjee T, Jaisankar P, Bandyopadhyay S. Rakshit S, et al. Among authors: jaisankar p. Biochem Pharmacol. 2010 Dec 1;80(11):1662-75. doi: 10.1016/j.bcp.2010.08.013. Epub 2010 Sep 9. Biochem Pharmacol. 2010. PMID: 20832390

7

Development of derivatives of 3, 3'-diindolylmethane as potent Leishmania donovani bi-subunit topoisomerase IB poisons.

Roy A, Chowdhury S, Sengupta S, Mandal M, Jaisankar P, D'Annessa I, Desideri A, Majumder HK. Roy A, et al. Among authors: jaisankar p. PLoS One. 2011;6(12):e28493. doi: 10.1371/journal.pone.0028493. Epub 2011 Dec 12. PLoS One. 2011. PMID: 22174820 Free PMC article.

8

Putralone, a novel 10alpha-hydroxy-25-nor D:A friedo-oleanane triterpenoid from Putranjiva roxburghii.

Mukherjee T, Sarkar T, Paul P, Chakraborty AK, Jaisankar P, Mukhopadhyay SB. Mukherjee T, et al. Among authors: jaisankar p. Nat Prod Commun. 2012 Apr;7(4):511-3. Nat Prod Commun. 2012. PMID: 22574455

9

Saracoside: a new lignan glycoside from Saraca indica, a potential inhibitor of DNA topoisomerase IB.

Mukherjee T, Chowdhury S, Kumar A, Majumder HK, Jaisankar P, Mukhopadhyay S. Mukherjee T, et al. Among authors: jaisankar p. Nat Prod Commun. 2012 Jun;7(6):767-9. Nat Prod Commun. 2012. PMID: 22816303

10

The lignan niranthin poisons Leishmania donovani topoisomerase IB and favours a Th1 immune response in mice.

Chowdhury S, Mukherjee T, Mukhopadhyay R, Mukherjee B, Sengupta S, Chattopadhyay S, Jaisankar P, Roy S, Majumder HK. Chowdhury S, et al. Among authors: jaisankar p. EMBO Mol Med. 2012 Oct;4(10):1126-43. doi: 10.1002/emmm.201201316. EMBO Mol Med. 2012. PMID: 23027614 Free PMC article.

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