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Vaccine-elicited human T cells recognizing conserved protein regions inhibit HIV-1.
Borthwick N, Ahmed T, Ondondo B, Hayes P, Rose A, Ebrahimsa U, Hayton EJ, Black A, Bridgeman A, Rosario M, Hill AV, Berrie E, Moyle S, Frahm N, Cox J, Colloca S, Nicosia A, Gilmour J, McMichael AJ, Dorrell L, Hanke T. Borthwick N, et al. Mol Ther. 2014 Feb;22(2):464-475. doi: 10.1038/mt.2013.248. Epub 2013 Oct 31. Mol Ther. 2014. PMID: 24166483 Free PMC article.
Long peptides induce polyfunctional T cells against conserved regions of HIV-1 with superior breadth to single-gene vaccines in macaques.
Rosario M, Bridgeman A, Quakkelaar ED, Quigley MF, Hill BJ, Knudsen ML, Ammendola V, Ljungberg K, Borthwick N, Im EJ, McMichael AJ, Drijfhout JW, Greenaway HY, Venturi V, Douek DC, Colloca S, Liljeström P, Nicosia A, Price DA, Melief CJ, Hanke T. Rosario M, et al. Among authors: borthwick n. Eur J Immunol. 2010 Jul;40(7):1973-84. doi: 10.1002/eji.201040344. Eur J Immunol. 2010. PMID: 20468055 Free article.
Broad HIV-1 inhibition in vitro by vaccine-elicited CD8(+) T cells in African adults.
Mutua G, Farah B, Langat R, Indangasi J, Ogola S, Onsembe B, Kopycinski JT, Hayes P, Borthwick NJ, Ashraf A, Dally L, Barin B, Tillander A, Gilmour J, De Bont J, Crook A, Hannaman D, Cox JH, Anzala O, Fast PE, Reilly M, Chinyenze K, Jaoko W, Hanke T, Hiv-Core 004 Study Group T. Mutua G, et al. Mol Ther Methods Clin Dev. 2016 Aug 31;3:16061. doi: 10.1038/mtm.2016.61. eCollection 2016. Mol Ther Methods Clin Dev. 2016. PMID: 27617268 Free PMC article.
PedVacc 002: a phase I/II randomized clinical trial of MVA.HIVA vaccine administered to infants born to human immunodeficiency virus type 1-positive mothers in Nairobi.
Njuguna IN, Ambler G, Reilly M, Ondondo B, Kanyugo M, Lohman-Payne B, Gichuhi C, Borthwick N, Black A, Mehedi SR, Sun J, Maleche-Obimbo E, Chohan B, John-Stewart GC, Jaoko W, Hanke T. Njuguna IN, et al. Among authors: borthwick n. Vaccine. 2014 Oct 7;32(44):5801-8. doi: 10.1016/j.vaccine.2014.08.034. Epub 2014 Aug 27. Vaccine. 2014. PMID: 25173484 Free PMC article. Clinical Trial.
Identification of novel HIV-1-derived HLA-E-binding peptides.
Hannoun Z, Lin Z, Brackenridge S, Kuse N, Akahoshi T, Borthwick N, McMichael A, Murakoshi H, Takiguchi M, Hanke T. Hannoun Z, et al. Among authors: borthwick n. Immunol Lett. 2018 Oct;202:65-72. doi: 10.1016/j.imlet.2018.08.005. Epub 2018 Aug 30. Immunol Lett. 2018. PMID: 30172717 Free PMC article.
94 results