Gustafsson MG - Search Results

1

Label-free detection and dynamic monitoring of drug-induced intracellular vesicle formation enabled using a 2-dimensional matched filter.

Aftab O, Fryknäs M, Zhang X, De Milito A, Hammerling U, Linder S, Larsson R, Gustafsson MG. Aftab O, et al. Among authors: gustafsson mg. Autophagy. 2014 Jan;10(1):57-69. doi: 10.4161/auto.26678. Epub 2013 Jan 1. Autophagy. 2014. PMID: 24169509 Free PMC article.

2

Label free high throughput screening for apoptosis inducing chemicals using time-lapse microscopy signal processing.

Aftab O, Nazir M, Fryknäs M, Hammerling U, Larsson R, Gustafsson MG. Aftab O, et al. Among authors: gustafsson mg. Apoptosis. 2014 Sep;19(9):1411-8. doi: 10.1007/s10495-014-1009-9. Apoptosis. 2014. PMID: 24923770

3

Detection of cell aggregation and altered cell viability by automated label-free video microscopy: a promising alternative to endpoint viability assays in high-throughput screening.

Aftab O, Fryknäs M, Hammerling U, Larsson R, Gustafsson MG. Aftab O, et al. Among authors: gustafsson mg. J Biomol Screen. 2015 Mar;20(3):372-81. doi: 10.1177/1087057114562158. Epub 2014 Dec 17. J Biomol Screen. 2015. PMID: 25520371

4

Screening for phenotype selective activity in multidrug resistant cells identifies a novel tubulin active agent insensitive to common forms of cancer drug resistance.

Fryknäs M, Gullbo J, Wang X, Rickardson L, Jarvius M, Wickström M, Hassan S, Andersson C, Gustafsson M, Westman G, Nygren P, Linder S, Larsson R. Fryknäs M, et al. BMC Cancer. 2013 Aug 6;13:374. doi: 10.1186/1471-2407-13-374. BMC Cancer. 2013. PMID: 23919498 Free PMC article.

5

Three-Dimensional Cell Culture-Based Screening Identifies the Anthelmintic Drug Nitazoxanide as a Candidate for Treatment of Colorectal Cancer.

Senkowski W, Zhang X, Olofsson MH, Isacson R, Höglund U, Gustafsson M, Nygren P, Linder S, Larsson R, Fryknäs M. Senkowski W, et al. Mol Cancer Ther. 2015 Jun;14(6):1504-16. doi: 10.1158/1535-7163.MCT-14-0792. Epub 2015 Apr 24. Mol Cancer Ther. 2015. PMID: 25911689 Free article.

6

In vitro drug sensitivity-gene expression correlations involve a tissue of origin dependency.

Andersson CR, Fryknäs M, Rickardson L, Larsson R, Isaksson A, Gustafsson MG. Andersson CR, et al. Among authors: gustafsson mg. J Chem Inf Model. 2007 Jan-Feb;47(1):239-48. doi: 10.1021/ci060073n. J Chem Inf Model. 2007. PMID: 17238270

7

In vitro discovery of promising anti-cancer drug combinations using iterative maximisation of a therapeutic index.

Kashif M, Andersson C, Hassan S, Karlsson H, Senkowski W, Fryknäs M, Nygren P, Larsson R, Gustafsson MG. Kashif M, et al. Among authors: gustafsson mg. Sci Rep. 2015 Sep 22;5:14118. doi: 10.1038/srep14118. Sci Rep. 2015. PMID: 26392291 Free PMC article.

8

A pragmatic definition of therapeutic synergy suitable for clinically relevant in vitro multicompound analyses.

Kashif M, Andersson C, Åberg M, Nygren P, Sjöblom T, Hammerling U, Larsson R, Gustafsson MG. Kashif M, et al. Among authors: gustafsson mg. Mol Cancer Ther. 2014 Jul;13(7):1964-76. doi: 10.1158/1535-7163.MCT-13-0430. Epub 2014 Apr 22. Mol Cancer Ther. 2014. PMID: 24755197

9

NMR spectroscopy-based metabolic profiling of drug-induced changes in vitro can discriminate between pharmacological classes.

Aftab O, Engskog MK, Haglöf J, Elmsjö A, Arvidsson T, Pettersson C, Hammerling U, Gustafsson MG. Aftab O, et al. Among authors: gustafsson mg. J Chem Inf Model. 2014 Nov 24;54(11):3251-8. doi: 10.1021/ci500502f. Epub 2014 Oct 30. J Chem Inf Model. 2014. PMID: 25321343

10

Assessing relative bioactivity of chemical substances using quantitative molecular network topology analysis.

Edberg A, Soeria-Atmadja D, Bergman Laurila J, Johansson F, Gustafsson MG, Hammerling U. Edberg A, et al. Among authors: gustafsson mg. J Chem Inf Model. 2012 May 25;52(5):1238-49. doi: 10.1021/ci200429f. Epub 2012 Apr 24. J Chem Inf Model. 2012. PMID: 22482822

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