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Discovery of a novel noniminosugar acid α glucosidase chaperone series.
Xiao J, Westbroek W, Motabar O, Lea WA, Hu X, Velayati A, Zheng W, Southall N, Gustafson AM, Goldin E, Sidransky E, Liu K, Simeonov A, Tamargo RJ, Ribes A, Matalonga L, Ferrer M, Marugan JJ. Xiao J, et al. Among authors: liu k. J Med Chem. 2012 Sep 13;55(17):7546-59. doi: 10.1021/jm3005543. Epub 2012 Aug 17. J Med Chem. 2012. PMID: 22834902 Free PMC article.
A high-throughput sphingomyelinase assay using natural substrate.
Xu M, Liu K, Southall N, Marugan JJ, Remaley AT, Zheng W. Xu M, et al. Among authors: liu k. Anal Bioanal Chem. 2012 Aug;404(2):407-14. doi: 10.1007/s00216-012-6174-5. Epub 2012 Jun 19. Anal Bioanal Chem. 2012. PMID: 22710568 Free PMC article.
δ-Tocopherol reduces lipid accumulation in Niemann-Pick type C1 and Wolman cholesterol storage disorders.
Xu M, Liu K, Swaroop M, Porter FD, Sidhu R, Firnkes S, Ory DS, Marugan JJ, Xiao J, Southall N, Pavan WJ, Davidson C, Walkley SU, Remaley AT, Baxa U, Sun W, McKew JC, Austin CP, Zheng W. Xu M, et al. Among authors: liu k. J Biol Chem. 2012 Nov 16;287(47):39349-60. doi: 10.1074/jbc.M112.357707. Epub 2012 Oct 3. J Biol Chem. 2012. PMID: 23035117 Free PMC article.
A novel brain penetrant NPS receptor antagonist, NCGC00185684, blocks alcohol-induced ERK-phosphorylation in the central amygdala and decreases operant alcohol self-administration in rats.
Thorsell A, Tapocik JD, Liu K, Zook M, Bell L, Flanigan M, Patnaik S, Marugan J, Damadzic R, Dehdashti SJ, Schwandt ML, Southall N, Austin CP, Eskay R, Ciccocioppo R, Zheng W, Heilig M. Thorsell A, et al. Among authors: liu k. J Neurosci. 2013 Jun 12;33(24):10132-42. doi: 10.1523/JNEUROSCI.4742-12.2013. J Neurosci. 2013. PMID: 23761908 Free PMC article.
A phenotypic compound screening assay for lysosomal storage diseases.
Xu M, Liu K, Swaroop M, Sun W, Dehdashti SJ, McKew JC, Zheng W. Xu M, et al. Among authors: liu k. J Biomol Screen. 2014 Jan;19(1):168-75. doi: 10.1177/1087057113501197. Epub 2013 Aug 27. J Biomol Screen. 2014. PMID: 23983233 Free PMC article.
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