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A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations.
Bønnelykke K, Sleiman P, Nielsen K, Kreiner-Møller E, Mercader JM, Belgrave D, den Dekker HT, Husby A, Sevelsted A, Faura-Tellez G, Mortensen LJ, Paternoster L, Flaaten R, Mølgaard A, Smart DE, Thomsen PF, Rasmussen MA, Bonàs-Guarch S, Holst C, Nohr EA, Yadav R, March ME, Blicher T, Lackie PM, Jaddoe VW, Simpson A, Holloway JW, Duijts L, Custovic A, Davies DE, Torrents D, Gupta R, Hollegaard MV, Hougaard DM, Hakonarson H, Bisgaard H. Bønnelykke K, et al. Among authors: faura tellez g. Nat Genet. 2014 Jan;46(1):51-5. doi: 10.1038/ng.2830. Epub 2013 Nov 17. Nat Genet. 2014. PMID: 24241537
Protocadherin-1 Localization and Cell-Adhesion Function in Airway Epithelial Cells in Asthma.
Faura Tellez G, Willemse BW, Brouwer U, Nijboer-Brinksma S, Vandepoele K, Noordhoek JA, Heijink I, de Vries M, Smithers NP, Postma DS, Timens W, Wiffen L, van Roy F, Holloway JW, Lackie PM, Nawijn MC, Koppelman GH. Faura Tellez G, et al. PLoS One. 2016 Oct 4;11(10):e0163967. doi: 10.1371/journal.pone.0163967. eCollection 2016. PLoS One. 2016. PMID: 27701444 Free PMC article.
Protocadherin-1 binds to SMAD3 and suppresses TGF-β1-induced gene transcription.
Faura Tellez G, Vandepoele K, Brouwer U, Koning H, Elderman RM, Hackett TL, Willemse BW, Holloway J, Van Roy F, Koppelman GH, Nawijn MC. Faura Tellez G, et al. Am J Physiol Lung Cell Mol Physiol. 2015 Oct 1;309(7):L725-35. doi: 10.1152/ajplung.00346.2014. Epub 2015 Jul 24. Am J Physiol Lung Cell Mol Physiol. 2015. PMID: 26209277 Free PMC article.