Spek CA - Search Results

1

CCAAT-enhancer binding protein delta (C/EBPδ) attenuates tubular injury and tubulointerstitial fibrogenesis during chronic obstructive nephropathy.

Duitman J, Borensztajn KS, Pulskens WP, Leemans JC, Florquin S, Spek CA. Duitman J, et al. Among authors: spek ca. Lab Invest. 2014 Jan;94(1):89-97. doi: 10.1038/labinvest.2013.127. Epub 2013 Nov 18. Lab Invest. 2014. PMID: 24247561 Free article.

2

Functional thrombomodulin deficiency causes enhanced thrombus growth in a murine model of carotid artery thrombosis.

Dörffler-Melly J, de Kruif M, Schwarte LA, Franco RF, Florquin S, Spek CA, Ince C, Reitsma PH, ten Cate H. Dörffler-Melly J, et al. Among authors: spek ca. Basic Res Cardiol. 2003 Nov;98(6):347-52. doi: 10.1007/s00395-003-0416-9. Epub 2003 May 12. Basic Res Cardiol. 2003. PMID: 14556079

3

Blood cell-derived tissue factor influences host response during murine endotoxemia.

Schoenmakers SH, Groot AP, Florquin S, Reitsma PH, Spek CA. Schoenmakers SH, et al. Among authors: spek ca. Blood Cells Mol Dis. 2004 Mar-Apr;32(2):325-33. doi: 10.1016/j.bcmd.2003.12.002. Blood Cells Mol Dis. 2004. PMID: 15003826

4

Inhibition of the tissue factor/factor VIIa pathway does not influence the inflammatory or antibacterial response to abdominal sepsis induced by Escherichia coli in mice.

Weijer S, Schoenmakers SH, Florquin S, Levi M, Vlasuk GP, Rote WE, Reitsma PH, Spek CA, van der Poll T. Weijer S, et al. Among authors: spek ca. J Infect Dis. 2004 Jun 15;189(12):2308-17. doi: 10.1086/421031. Epub 2004 May 25. J Infect Dis. 2004. PMID: 15181580

5

Local activation of the tissue factor-factor VIIa pathway in patients with pneumonia and the effect of inhibition of this pathway in murine pneumococcal pneumonia.

Rijneveld AW, Weijer S, Bresser P, Florquin S, Vlasuk GP, Rote WE, Spek CA, Reitsma PH, van der Zee JS, Levi M, van der Poll T. Rijneveld AW, et al. Among authors: spek ca. Crit Care Med. 2006 Jun;34(6):1725-30. doi: 10.1097/01.CCM.0000218807.20570.C2. Crit Care Med. 2006. PMID: 16625114

6

Coagulation factor Xa drives tumor cells into apoptosis through BH3-only protein Bim up-regulation.

Borensztajn KS, Bijlsma MF, Groot AP, Brüggemann LW, Versteeg HH, Reitsma PH, Peppelenbosch MP, Spek CA. Borensztajn KS, et al. Among authors: spek ca. Exp Cell Res. 2007 Jul 15;313(12):2622-33. doi: 10.1016/j.yexcr.2007.04.014. Epub 2007 Apr 19. Exp Cell Res. 2007. PMID: 17531220

7

Sonic hedgehog induces transcription-independent cytoskeletal rearrangement and migration regulated by arachidonate metabolites.

Bijlsma MF, Borensztajn KS, Roelink H, Peppelenbosch MP, Spek CA. Bijlsma MF, et al. Among authors: spek ca. Cell Signal. 2007 Dec;19(12):2596-604. doi: 10.1016/j.cellsig.2007.08.011. Epub 2007 Aug 24. Cell Signal. 2007. PMID: 17884337

8

Factor Xa stimulates proinflammatory and profibrotic responses in fibroblasts via protease-activated receptor-2 activation.

Borensztajn K, Stiekema J, Nijmeijer S, Reitsma PH, Peppelenbosch MP, Spek CA. Borensztajn K, et al. Among authors: spek ca. Am J Pathol. 2008 Feb;172(2):309-20. doi: 10.2353/ajpath.2008.070347. Epub 2008 Jan 17. Am J Pathol. 2008. PMID: 18202198 Free PMC article.

9

TF:FVIIa-specific activation of CREB upregulates proapoptotic proteins via protease-activated receptor-2.

Versteeg HH, Borensztajn KS, Kerver ME, Ruf W, Reitsma PH, Spek CA, Peppelenbosch MP. Versteeg HH, et al. Among authors: spek ca. J Thromb Haemost. 2008 Sep;6(9):1550-7. doi: 10.1111/j.1538-7836.2008.03091.x. Epub 2008 Jul 19. J Thromb Haemost. 2008. PMID: 18647225 Free article.

10

Factor Xa: at the crossroads between coagulation and signaling in physiology and disease.

Borensztajn K, Peppelenbosch MP, Spek CA. Borensztajn K, et al. Among authors: spek ca. Trends Mol Med. 2008 Oct;14(10):429-40. doi: 10.1016/j.molmed.2008.08.001. Epub 2008 Sep 4. Trends Mol Med. 2008. PMID: 18774340 Review.

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