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Farnesoid X receptor activation by the novel agonist TC-100 (3α, 7α, 11β-Trihydroxy-6α-ethyl-5β-cholan-24-oic Acid) preserves the intestinal barrier integrity and promotes intestinal microbial reshaping in a mouse model of obstructed bile acid flow.
Marzano M, Fosso B, Colliva C, Notario E, Passeri D, Intranuovo M, Gioiello A, Adorini L, Pesole G, Pellicciari R, Moschetta A, Gadaleta RM. Marzano M, et al. Among authors: colliva c. Biomed Pharmacother. 2022 Sep;153:113380. doi: 10.1016/j.biopha.2022.113380. Epub 2022 Jul 19. Biomed Pharmacother. 2022. PMID: 36076475 Free article.
Identification and quantification of glucosamine in rabbit cartilage and correlation with plasma levels by high performance liquid chromatography-electrospray ionization-tandem mass spectrometry.
Pastorini E, Vecchiotti S, Colliva C, Persiani S, Rotini R, Roatti G, Zaccarelli L, Rovati LC, Roda A. Pastorini E, et al. Among authors: colliva c. Anal Chim Acta. 2011 Jun 10;695(1-2):77-83. doi: 10.1016/j.aca.2011.04.003. Epub 2011 Apr 12. Anal Chim Acta. 2011. PMID: 21601033
Ablation of liver Fxr results in an increased colonic mucus barrier in mice.
Ijssennagger N, van Rooijen KS, Magnúsdóttir S, Ramos Pittol JM, Willemsen ECL, de Zoete MR, Baars MJD, Stege PB, Colliva C, Pellicciari R, Youssef SA, de Bruin A, Vercoulen Y, Kuipers F, van Mil SWC. Ijssennagger N, et al. Among authors: colliva c. JHEP Rep. 2021 Aug 4;3(5):100344. doi: 10.1016/j.jhepr.2021.100344. eCollection 2021 Oct. JHEP Rep. 2021. PMID: 34604725 Free PMC article.
Discovery of 3α,7α,11β-Trihydroxy-6α-ethyl-5β-cholan-24-oic Acid (TC-100), a Novel Bile Acid as Potent and Highly Selective FXR Agonist for Enterohepatic Disorders.
Pellicciari R, Passeri D, De Franco F, Mostarda S, Filipponi P, Colliva C, Gadaleta RM, Franco P, Carotti A, Macchiarulo A, Roda A, Moschetta A, Gioiello A. Pellicciari R, et al. Among authors: colliva c. J Med Chem. 2016 Oct 13;59(19):9201-9214. doi: 10.1021/acs.jmedchem.6b01126. Epub 2016 Oct 4. J Med Chem. 2016. PMID: 27652492
30 results