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Thymic medullary epithelium and thymocyte self-tolerance require cooperation between CD28-CD80/86 and CD40-CD40L costimulatory pathways.
Williams JA, Zhang J, Jeon H, Nitta T, Ohigashi I, Klug D, Kruhlak MJ, Choudhury B, Sharrow SO, Granger L, Adams A, Eckhaus MA, Jenkinson SR, Richie ER, Gress RE, Takahama Y, Hodes RJ. Williams JA, et al. Among authors: sharrow so. J Immunol. 2014 Jan 15;192(2):630-40. doi: 10.4049/jimmunol.1302550. Epub 2013 Dec 13. J Immunol. 2014. PMID: 24337745 Free PMC article.
TRAF3 enforces the requirement for T cell cross-talk in thymic medullary epithelial development.
Jenkinson SR, Williams JA, Jeon H, Zhang J, Nitta T, Ohigashi I, Kruhlak M, Zuklys S, Sharrow S, Adams A, Granger L, Choi Y, Siebenlist U, Bishop GA, Hollander GA, Takahama Y, Hodes RJ. Jenkinson SR, et al. Among authors: sharrow s. Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21107-12. doi: 10.1073/pnas.1314859111. Epub 2013 Dec 9. Proc Natl Acad Sci U S A. 2013. PMID: 24324158 Free PMC article.
176 results