Timmers HT - Search Results

1

A novel microscopy-based high-throughput screening method to identify proteins that regulate global histone modification levels.

Baas R, Lelieveld D, van Teeffelen H, Lijnzaad P, Castelijns B, van Schaik FM, Vermeulen M, Egan DA, Timmers HT, de Graaf P. Baas R, et al. Among authors: timmers ht. J Biomol Screen. 2014 Feb;19(2):287-96. doi: 10.1177/1087057113515024. Epub 2013 Dec 11. J Biomol Screen. 2014. PMID: 24334265

2

A dual role for SAGA-associated factor 29 (SGF29) in ER stress survival by coordination of both histone H3 acetylation and histone H3 lysine-4 trimethylation.

Schram AW, Baas R, Jansen PW, Riss A, Tora L, Vermeulen M, Timmers HT. Schram AW, et al. Among authors: timmers ht. PLoS One. 2013 Jul 23;8(7):e70035. doi: 10.1371/journal.pone.0070035. Print 2013. PLoS One. 2013. PMID: 23894581 Free PMC article.

3

Cell cycle regulation by the PRMT6 arginine methyltransferase through repression of cyclin-dependent kinase inhibitors.

Kleinschmidt MA, de Graaf P, van Teeffelen HA, Timmers HT. Kleinschmidt MA, et al. Among authors: timmers ht. PLoS One. 2012;7(8):e41446. doi: 10.1371/journal.pone.0041446. Epub 2012 Aug 20. PLoS One. 2012. PMID: 22916108 Free PMC article.

4

The mixed lineage leukemia 4 (MLL4) methyltransferase complex is involved in transforming growth factor beta (TGF-β)-activated gene transcription.

Baas R, van Teeffelen HAAM, Tjalsma SJD, Timmers HTM. Baas R, et al. Transcription. 2018;9(2):67-74. doi: 10.1080/21541264.2017.1373890. Epub 2017 Nov 3. Transcription. 2018. PMID: 28976802 Free PMC article.

5

Involvement of the SMRT/NCoR-HDAC3 complex in transcriptional repression by the CNOT2 subunit of the human Ccr4-Not complex.

Jayne S, Zwartjes CG, van Schaik FM, Timmers HT. Jayne S, et al. Among authors: timmers ht. Biochem J. 2006 Sep 15;398(3):461-7. doi: 10.1042/BJ20060406. Biochem J. 2006. PMID: 16712523 Free PMC article.

6

Structural insight into the recognition of the H3K4me3 mark by the TFIID subunit TAF3.

van Ingen H, van Schaik FM, Wienk H, Ballering J, Rehmann H, Dechesne AC, Kruijzer JA, Liskamp RM, Timmers HT, Boelens R. van Ingen H, et al. Among authors: timmers ht. Structure. 2008 Aug 6;16(8):1245-56. doi: 10.1016/j.str.2008.04.015. Structure. 2008. PMID: 18682226 Free article.

7

Chromatin interaction of TATA-binding protein is dynamically regulated in human cells.

de Graaf P, Mousson F, Geverts B, Scheer E, Tora L, Houtsmuller AB, Timmers HT. de Graaf P, et al. Among authors: timmers ht. J Cell Sci. 2010 Aug 1;123(Pt 15):2663-71. doi: 10.1242/jcs.064097. Epub 2010 Jul 13. J Cell Sci. 2010. PMID: 20627952

8

Mutational analysis of BTAF1-TBP interaction: BTAF1 can rescue DNA-binding defective TBP mutants.

Klejman MP, Zhao X, van Schaik FM, Herr W, Timmers HT. Klejman MP, et al. Among authors: timmers ht. Nucleic Acids Res. 2005 Sep 22;33(17):5426-36. doi: 10.1093/nar/gki850. Print 2005. Nucleic Acids Res. 2005. PMID: 16179647 Free PMC article.

9

Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4.

Vermeulen M, Mulder KW, Denissov S, Pijnappel WW, van Schaik FM, Varier RA, Baltissen MP, Stunnenberg HG, Mann M, Timmers HT. Vermeulen M, et al. Among authors: timmers ht. Cell. 2007 Oct 5;131(1):58-69. doi: 10.1016/j.cell.2007.08.016. Epub 2007 Sep 20. Cell. 2007. PMID: 17884155 Free article.

10

Human Ccr4-Not complexes contain variable deadenylase subunits.

Lau NC, Kolkman A, van Schaik FM, Mulder KW, Pijnappel WW, Heck AJ, Timmers HT. Lau NC, et al. Among authors: timmers ht. Biochem J. 2009 Aug 27;422(3):443-53. doi: 10.1042/BJ20090500. Biochem J. 2009. PMID: 19558367

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