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Rho GTPases and cancer.
Li H, Peyrollier K, Kilic G, Brakebusch C. Li H, et al. Among authors: brakebusch c. Biofactors. 2014 Mar-Apr;40(2):226-35. doi: 10.1002/biof.1155. Epub 2013 Dec 21. Biofactors. 2014. PMID: 24375503 Review.
Rho GTPase function in tumorigenesis.
Karlsson R, Pedersen ED, Wang Z, Brakebusch C. Karlsson R, et al. Among authors: brakebusch c. Biochim Biophys Acta. 2009 Dec;1796(2):91-8. doi: 10.1016/j.bbcan.2009.03.003. Epub 2009 Mar 24. Biochim Biophys Acta. 2009. PMID: 19327386 Review.
RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes.
Jackson B, Peyrollier K, Pedersen E, Basse A, Karlsson R, Wang Z, Lefever T, Ochsenbein AM, Schmidt G, Aktories K, Stanley A, Quondamatteo F, Ladwein M, Rottner K, van Hengel J, Brakebusch C. Jackson B, et al. Among authors: brakebusch c. Mol Biol Cell. 2011 Mar 1;22(5):593-605. doi: 10.1091/mbc.E09-10-0859. Epub 2011 Jan 5. Mol Biol Cell. 2011. PMID: 21209320 Free PMC article.
Mouse macrophages completely lacking Rho subfamily GTPases (RhoA, RhoB, and RhoC) have severe lamellipodial retraction defects, but robust chemotactic navigation and altered motility.
Königs V, Jennings R, Vogl T, Horsthemke M, Bachg AC, Xu Y, Grobe K, Brakebusch C, Schwab A, Bähler M, Knaus UG, Hanley PJ. Königs V, et al. Among authors: brakebusch c. J Biol Chem. 2014 Oct 31;289(44):30772-30784. doi: 10.1074/jbc.M114.563270. Epub 2014 Sep 11. J Biol Chem. 2014. PMID: 25213860 Free PMC article.
191 results