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Page 1
Transient non-native hydrogen bonds promote activation of a signaling protein.
Gardino AK, Villali J, Kivenson A, Lei M, Liu CF, Steindel P, Eisenmesser EZ, Labeikovsky W, Wolf-Watz M, Clarkson MW, Kern D. Gardino AK, et al. Among authors: villali j. Cell. 2009 Dec 11;139(6):1109-18. doi: 10.1016/j.cell.2009.11.022. Cell. 2009. PMID: 20005804 Free PMC article.
Choreographing an enzyme's dance.
Villali J, Kern D. Villali J, et al. Curr Opin Chem Biol. 2010 Oct;14(5):636-43. doi: 10.1016/j.cbpa.2010.08.007. Epub 2010 Sep 6. Curr Opin Chem Biol. 2010. PMID: 20822946 Free PMC article. Review.
Ancient origins of allosteric activation in a Ser-Thr kinase.
Hadzipasic A, Wilson C, Nguyen V, Kern N, Kim C, Pitsawong W, Villali J, Zheng Y, Kern D. Hadzipasic A, et al. Among authors: villali j. Science. 2020 Feb 21;367(6480):912-917. doi: 10.1126/science.aay9959. Science. 2020. PMID: 32079772 Free PMC article.
Quantitative modeling predicts competitive advantages of a next generation anti-NKG2A monoclonal antibody over monalizumab for the treatment of cancer.
Spinosa P, Musial-Siwek M, Presler M, Betts A, Rosentrater E, Villali J, Wille L, Zhao Y, McCaughtry T, Subramanian K, Liu H. Spinosa P, et al. Among authors: villali j. CPT Pharmacometrics Syst Pharmacol. 2021 Mar;10(3):220-229. doi: 10.1002/psp4.12592. Epub 2021 Feb 13. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 33501768 Free PMC article.