Steelman LS - Search Results

1

Inhibition of GSK-3β activity can result in drug and hormonal resistance and alter sensitivity to targeted therapy in MCF-7 breast cancer cells.

Sokolosky M, Chappell WH, Stadelman K, Abrams SL, Davis NM, Steelman LS, McCubrey JA. Sokolosky M, et al. Among authors: steelman ls. Cell Cycle. 2014;13(5):820-33. doi: 10.4161/cc.27728. Epub 2014 Jan 9. Cell Cycle. 2014. PMID: 24407515 Free PMC article.

2

Raf-induced cell cycle progression in human TF-1 hematopoietic cells.

Chang F, Steelman LS, McCubrey JA. Chang F, et al. Among authors: steelman ls. Cell Cycle. 2002 May-Jun;1(3):220-6. Cell Cycle. 2002. PMID: 12429936

3

B-raf and insulin synergistically prevent apoptosis and induce cell cycle progression in hematopoietic cells.

Shelton JG, Chang F, Lee JT, Franklin RA, Steelman LS, McCubrey JA. Shelton JG, et al. Among authors: steelman ls. Cell Cycle. 2004 Feb;3(2):189-96. Cell Cycle. 2004. PMID: 14712088

4

Synergy between PI3K/Akt and Raf/MEK/ERK pathways in IGF-1R mediated cell cycle progression and prevention of apoptosis in hematopoietic cells.

Shelton JG, Steelman LS, White ER, McCubrey JA. Shelton JG, et al. Among authors: steelman ls. Cell Cycle. 2004 Mar;3(3):372-9. Epub 2004 Mar 1. Cell Cycle. 2004. PMID: 14726697

5

Ability of the activated PI3K/Akt oncoproteins to synergize with MEK1 and induce cell cycle progression and abrogate the cytokine-dependence of hematopoietic cells.

Shelton JG, Blalock WL, White ER, Steelman LS, McCubrey JA. Shelton JG, et al. Among authors: steelman ls. Cell Cycle. 2004 Apr;3(4):503-12. Epub 2004 Apr 1. Cell Cycle. 2004. PMID: 15004527

6

Akt inactivates ERK causing decreased response to chemotherapeutic drugs in advanced CaP cells.

Lee JT, Steelman LS, Chappell WH, McCubrey JA. Lee JT, et al. Among authors: steelman ls. Cell Cycle. 2008 Mar 1;7(5):631-6. doi: 10.4161/cc.7.5.5416. Epub 2007 Dec 6. Cell Cycle. 2008. PMID: 18256541

7

Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy.

McCubrey JA, Sokolosky ML, Lehmann BD, Taylor JR, Navolanic PM, Chappell WH, Abrams SL, Stadelman KM, Wong EW, Misaghian N, Horn S, Bäsecke J, Libra M, Stivala F, Ligresti G, Tafuri A, Milella M, Zarzycki M, Dzugaj A, Chiarini F, Evangelisti C, Martelli AM, Terrian DM, Franklin RA, Steelman LS. McCubrey JA, et al. Among authors: steelman ls. Adv Enzyme Regul. 2008;48:113-35. doi: 10.1016/j.advenzreg.2008.02.006. Epub 2008 Feb 21. Adv Enzyme Regul. 2008. PMID: 18423407 Free PMC article.

8

Targeting prostate cancer based on signal transduction and cell cycle pathways.

Lee JT, Lehmann BD, Terrian DM, Chappell WH, Stivala F, Libra M, Martelli AM, Steelman LS, McCubrey JA. Lee JT, et al. Among authors: steelman ls. Cell Cycle. 2008 Jun 15;7(12):1745-62. doi: 10.4161/cc.7.12.6166. Epub 2008 Jun 16. Cell Cycle. 2008. PMID: 18594202 Free PMC article. Review.

9

Akt as a therapeutic target in cancer.

Steelman LS, Stadelman KM, Chappell WH, Horn S, Bäsecke J, Cervello M, Nicoletti F, Libra M, Stivala F, Martelli AM, McCubrey JA. Steelman LS, et al. Expert Opin Ther Targets. 2008 Sep;12(9):1139-65. doi: 10.1517/14728222.12.9.1139. Expert Opin Ther Targets. 2008. PMID: 18694380 Review.

10

Dominant roles of the Raf/MEK/ERK pathway in cell cycle progression, prevention of apoptosis and sensitivity to chemotherapeutic drugs.

Steelman LS, Abrams SL, Shelton JG, Chappell WH, Bäsecke J, Stivala F, Donia M, Nicoletti F, Libra M, Martelli AM, McCubrey JA. Steelman LS, et al. Cell Cycle. 2010 Apr 15;9(8):1629-38. doi: 10.4161/cc.9.8.11487. Epub 2010 Apr 15. Cell Cycle. 2010. PMID: 20372086 Free PMC article.

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