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Regression of metastatic Merkel cell carcinoma following transfer of polyomavirus-specific T cells and therapies capable of re-inducing HLA class-I.
Chapuis AG, Afanasiev OK, Iyer JG, Paulson KG, Parvathaneni U, Hwang JH, Lai I, Roberts IM, Sloan HL, Bhatia S, Shibuya KC, Gooley T, Desmarais C, Koelle DM, Yee C, Nghiem P. Chapuis AG, et al. Among authors: koelle dm. Cancer Immunol Res. 2014 Jan;2(1):27-36. doi: 10.1158/2326-6066.CIR-13-0087. Cancer Immunol Res. 2014. PMID: 24432305 Free PMC article.
Autoreactive T cells in healthy individuals.
Danke NA, Koelle DM, Yee C, Beheray S, Kwok WW. Danke NA, et al. Among authors: koelle dm. J Immunol. 2004 May 15;172(10):5967-72. doi: 10.4049/jimmunol.172.10.5967. J Immunol. 2004. PMID: 15128778
Transcriptome-wide studies of merkel cell carcinoma and validation of intratumoral CD8+ lymphocyte invasion as an independent predictor of survival.
Paulson KG, Iyer JG, Tegeder AR, Thibodeau R, Schelter J, Koba S, Schrama D, Simonson WT, Lemos BD, Byrd DR, Koelle DM, Galloway DA, Leonard JH, Madeleine MM, Argenyi ZB, Disis ML, Becker JC, Cleary MA, Nghiem P. Paulson KG, et al. Among authors: koelle dm. J Clin Oncol. 2011 Apr 20;29(12):1539-46. doi: 10.1200/JCO.2010.30.6308. Epub 2011 Mar 21. J Clin Oncol. 2011. PMID: 21422430 Free PMC article.
Merkel cell polyomavirus-specific CD8⁺ and CD4⁺ T-cell responses identified in Merkel cell carcinomas and blood.
Iyer JG, Afanasiev OK, McClurkan C, Paulson K, Nagase K, Jing L, Marshak JO, Dong L, Carter J, Lai I, Farrar E, Byrd D, Galloway D, Yee C, Koelle DM, Nghiem P. Iyer JG, et al. Among authors: koelle dm. Clin Cancer Res. 2011 Nov 1;17(21):6671-80. doi: 10.1158/1078-0432.CCR-11-1513. Epub 2011 Sep 9. Clin Cancer Res. 2011. PMID: 21908576 Free PMC article.
Downregulation of MHC-I expression is prevalent but reversible in Merkel cell carcinoma.
Paulson KG, Tegeder A, Willmes C, Iyer JG, Afanasiev OK, Schrama D, Koba S, Thibodeau R, Nagase K, Simonson WT, Seo A, Koelle DM, Madeleine M, Bhatia S, Nakajima H, Sano S, Hardwick JS, Disis ML, Cleary MA, Becker JC, Nghiem P. Paulson KG, et al. Among authors: koelle dm. Cancer Immunol Res. 2014 Nov;2(11):1071-9. doi: 10.1158/2326-6066.CIR-14-0005. Epub 2014 Aug 12. Cancer Immunol Res. 2014. PMID: 25116754 Free PMC article.
Tumor-Infiltrating Merkel Cell Polyomavirus-Specific T Cells Are Diverse and Associated with Improved Patient Survival.
Miller NJ, Church CD, Dong L, Crispin D, Fitzgibbon MP, Lachance K, Jing L, Shinohara M, Gavvovidis I, Willimsky G, McIntosh M, Blankenstein T, Koelle DM, Nghiem P. Miller NJ, et al. Among authors: koelle dm. Cancer Immunol Res. 2017 Feb;5(2):137-147. doi: 10.1158/2326-6066.CIR-16-0210. Epub 2017 Jan 16. Cancer Immunol Res. 2017. PMID: 28093446 Free PMC article.
Intratumoral G100, a TLR4 Agonist, Induces Antitumor Immune Responses and Tumor Regression in Patients with Merkel Cell Carcinoma.
Bhatia S, Miller NJ, Lu H, Longino NV, Ibrani D, Shinohara MM, Byrd DR, Parvathaneni U, Kulikauskas R, Ter Meulen J, Hsu FJ, Koelle DM, Nghiem P. Bhatia S, et al. Among authors: koelle dm. Clin Cancer Res. 2019 Feb 15;25(4):1185-1195. doi: 10.1158/1078-0432.CCR-18-0469. Epub 2018 Aug 9. Clin Cancer Res. 2019. PMID: 30093453 Free PMC article. Clinical Trial.
235 results