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The secreted protein ANGPTL2 promotes metastasis of osteosarcoma cells through integrin α5β1, p38 MAPK, and matrix metalloproteinases.
Odagiri H, Kadomatsu T, Endo M, Masuda T, Morioka MS, Fukuhara S, Miyamoto T, Kobayashi E, Miyata K, Aoi J, Horiguchi H, Nishimura N, Terada K, Yakushiji T, Manabe I, Mochizuki N, Mizuta H, Oike Y. Odagiri H, et al. Among authors: kobayashi e. Sci Signal. 2014 Jan 21;7(309):ra7. doi: 10.1126/scisignal.2004612. Sci Signal. 2014. PMID: 24448647
Twist2 functions as a tumor suppressor in murine osteosarcoma cells.
Ishikawa T, Shimizu T, Ueki A, Yamaguchi SI, Onishi N, Sugihara E, Kuninaka S, Miyamoto T, Morioka H, Nakayama R, Kobayashi E, Toyama Y, Mabuchi Y, Matsuzaki Y, Yamaguchi R, Miyano S, Saya H. Ishikawa T, et al. Among authors: kobayashi e. Cancer Sci. 2013 Jul;104(7):880-8. doi: 10.1111/cas.12163. Epub 2013 May 9. Cancer Sci. 2013. PMID: 23557174 Free PMC article.
The IL-17-IL-17RA axis is required to promote osteosarcoma progression in mice.
Yoshimura N, Kariya R, Shimada M, Tateyama M, Matsunaga H, Shibata Y, Tanimura S, Takata K, Arima T, Kawakami J, Maeda K, Fukuma Y, Uragami M, Ideo K, Sugimoto K, Yonemitsu R, Matsushita K, Hisanaga S, Yugami M, Uehara Y, Masuda T, Nakamura T, Tokunaga T, Karasugi T, Sueyoshi T, Sato H, Iwakura Y, Araki K, Kobayashi E, Okada S, Miyamoto T. Yoshimura N, et al. Among authors: kobayashi e. Sci Rep. 2023 Dec 7;13(1):21572. doi: 10.1038/s41598-023-49016-1. Sci Rep. 2023. PMID: 38062130 Free PMC article.
Functional genome screen for therapeutic targets of osteosarcoma.
Yamaguchi U, Honda K, Satow R, Kobayashi E, Nakayama R, Ichikawa H, Shoji A, Shitashige M, Masuda M, Kawai A, Chuman H, Iwamoto Y, Hirohashi S, Yamada T. Yamaguchi U, et al. Among authors: kobayashi e. Cancer Sci. 2009 Dec;100(12):2268-74. doi: 10.1111/j.1349-7006.2009.01310.x. Epub 2009 Aug 10. Cancer Sci. 2009. PMID: 19725836 Free PMC article.
Clinical relevance and therapeutic significance of microRNA-133a expression profiles and functions in malignant osteosarcoma-initiating cells.
Fujiwara T, Katsuda T, Hagiwara K, Kosaka N, Yoshioka Y, Takahashi RU, Takeshita F, Kubota D, Kondo T, Ichikawa H, Yoshida A, Kobayashi E, Kawai A, Ozaki T, Ochiya T. Fujiwara T, et al. Among authors: kobayashi e. Stem Cells. 2014 Apr;32(4):959-73. doi: 10.1002/stem.1618. Stem Cells. 2014. PMID: 24715690 Clinical Trial.
Clinical significance of circulating miR-25-3p as a novel diagnostic and prognostic biomarker in osteosarcoma.
Fujiwara T, Uotani K, Yoshida A, Morita T, Nezu Y, Kobayashi E, Yoshida A, Uehara T, Omori T, Sugiu K, Komatsubara T, Takeda K, Kunisada T, Kawamura M, Kawai A, Ochiya T, Ozaki T. Fujiwara T, et al. Among authors: kobayashi e. Oncotarget. 2017 May 16;8(20):33375-33392. doi: 10.18632/oncotarget.16498. Oncotarget. 2017. PMID: 28380419 Free PMC article.
1,855 results