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The secreted protein ANGPTL2 promotes metastasis of osteosarcoma cells through integrin α5β1, p38 MAPK, and matrix metalloproteinases.
Odagiri H, Kadomatsu T, Endo M, Masuda T, Morioka MS, Fukuhara S, Miyamoto T, Kobayashi E, Miyata K, Aoi J, Horiguchi H, Nishimura N, Terada K, Yakushiji T, Manabe I, Mochizuki N, Mizuta H, Oike Y. Odagiri H, et al. Among authors: oike y. Sci Signal. 2014 Jan 21;7(309):ra7. doi: 10.1126/scisignal.2004612. Sci Signal. 2014. PMID: 24448647
Angiopoietin-related growth factor antagonizes obesity and insulin resistance.
Oike Y, Akao M, Yasunaga K, Yamauchi T, Morisada T, Ito Y, Urano T, Kimura Y, Kubota Y, Maekawa H, Miyamoto T, Miyata K, Matsumoto S, Sakai J, Nakagata N, Takeya M, Koseki H, Ogawa Y, Kadowaki T, Suda T. Oike Y, et al. Nat Med. 2005 Apr;11(4):400-8. doi: 10.1038/nm1214. Epub 2005 Mar 20. Nat Med. 2005. PMID: 15778720 Free article.
Elevated mature macrophage expression of human ABHD2 gene in vulnerable plaque.
Miyata K, Nakayama M, Mizuta S, Hokimoto S, Sugamura K, Oshima S, Oike Y, Sugiyama S, Ogawa H, Yamamura K. Miyata K, et al. Among authors: oike y. Biochem Biophys Res Commun. 2008 Jan 11;365(2):207-13. doi: 10.1016/j.bbrc.2007.10.127. Epub 2007 Oct 31. Biochem Biophys Res Commun. 2008. PMID: 17980156
Angiopoietin-related growth factor enhances blood flow via activation of the ERK1/2-eNOS-NO pathway in a mouse hind-limb ischemia model.
Urano T, Ito Y, Akao M, Sawa T, Miyata K, Tabata M, Morisada T, Hato T, Yano M, Kadomatsu T, Yasunaga K, Shibata R, Murohara T, Akaike T, Tanihara H, Suda T, Oike Y. Urano T, et al. Among authors: oike y. Arterioscler Thromb Vasc Biol. 2008 May;28(5):827-34. doi: 10.1161/ATVBAHA.107.149674. Epub 2008 Feb 7. Arterioscler Thromb Vasc Biol. 2008. PMID: 18258819
Angptl 4 deficiency improves lipid metabolism, suppresses foam cell formation and protects against atherosclerosis.
Adachi H, Fujiwara Y, Kondo T, Nishikawa T, Ogawa R, Matsumura T, Ishii N, Nagai R, Miyata K, Tabata M, Motoshima H, Furukawa N, Tsuruzoe K, Kawashima J, Takeya M, Yamashita S, Koh GY, Nagy A, Suda T, Oike Y, Araki E. Adachi H, et al. Among authors: oike y. Biochem Biophys Res Commun. 2009 Feb 20;379(4):806-11. doi: 10.1016/j.bbrc.2008.12.018. Epub 2008 Dec 16. Biochem Biophys Res Commun. 2009. PMID: 19094966
298 results