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Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival.
Gjerdrum C, Tiron C, Høiby T, Stefansson I, Haugen H, Sandal T, Collett K, Li S, McCormack E, Gjertsen BT, Micklem DR, Akslen LA, Glackin C, Lorens JB. Gjerdrum C, et al. Among authors: hoiby t. Proc Natl Acad Sci U S A. 2010 Jan 19;107(3):1124-9. doi: 10.1073/pnas.0909333107. Epub 2009 Dec 28. Proc Natl Acad Sci U S A. 2010. PMID: 20080645 Free PMC article.
A facelift for the general transcription factor TFIIA.
Høiby T, Zhou H, Mitsiou DJ, Stunnenberg HG. Høiby T, et al. Biochim Biophys Acta. 2007 Jul-Aug;1769(7-8):429-36. doi: 10.1016/j.bbaexp.2007.04.008. Epub 2007 May 5. Biochim Biophys Acta. 2007. PMID: 17560669 Review.
Uncleaved TFIIA is a substrate for taspase 1 and active in transcription.
Zhou H, Spicuglia S, Hsieh JJ, Mitsiou DJ, Høiby T, Veenstra GJ, Korsmeyer SJ, Stunnenberg HG. Zhou H, et al. Among authors: hoiby t. Mol Cell Biol. 2006 Apr;26(7):2728-35. doi: 10.1128/MCB.26.7.2728-2735.2006. Mol Cell Biol. 2006. PMID: 16537915 Free PMC article.