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Metabolic inhibitors accentuate the anti-tumoral effect of HDAC5 inhibition.
Hendrick E, Peixoto P, Blomme A, Polese C, Matheus N, Cimino J, Frère A, Mouithys-Mickalad A, Serteyn D, Bettendorff L, Elmoualij B, De Tullio P, Eppe G, Dequiedt F, Castronovo V, Mottet D. Hendrick E, et al. Among authors: peixoto p. Oncogene. 2017 Aug 24;36(34):4859-4874. doi: 10.1038/onc.2017.103. Epub 2017 Apr 17. Oncogene. 2017. PMID: 28414307 Free article.
Myoferlin is a key regulator of EGFR activity in breast cancer.
Turtoi A, Blomme A, Bellahcène A, Gilles C, Hennequière V, Peixoto P, Bianchi E, Noel A, De Pauw E, Lifrange E, Delvenne P, Castronovo V. Turtoi A, et al. Among authors: peixoto p. Cancer Res. 2013 Sep 1;73(17):5438-48. doi: 10.1158/0008-5472.CAN-13-1142. Epub 2013 Jul 17. Cancer Res. 2013. PMID: 23864327 Free article.
PP2A regulatory subunit Bα controls endothelial contractility and vessel lumen integrity via regulation of HDAC7.
Martin M, Geudens I, Bruyr J, Potente M, Bleuart A, Lebrun M, Simonis N, Deroanne C, Twizere JC, Soubeyran P, Peixoto P, Mottet D, Janssens V, Hofmann WK, Claes F, Carmeliet P, Kettmann R, Gerhardt H, Dequiedt F. Martin M, et al. Among authors: peixoto p. EMBO J. 2013 Sep 11;32(18):2491-503. doi: 10.1038/emboj.2013.187. Epub 2013 Aug 16. EMBO J. 2013. PMID: 23955003 Free PMC article.
Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis.
Nokin MJ, Durieux F, Peixoto P, Chiavarina B, Peulen O, Blomme A, Turtoi A, Costanza B, Smargiasso N, Baiwir D, Scheijen JL, Schalkwijk CG, Leenders J, De Tullio P, Bianchi E, Thiry M, Uchida K, Spiegel DA, Cochrane JR, Hutton CA, De Pauw E, Delvenne P, Belpomme D, Castronovo V, Bellahcène A. Nokin MJ, et al. Among authors: peixoto p. Elife. 2016 Oct 19;5:e19375. doi: 10.7554/eLife.19375. Elife. 2016. PMID: 27759563 Free PMC article.
238 results