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Page 1
Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling.
Felcht M, Luck R, Schering A, Seidel P, Srivastava K, Hu J, Bartol A, Kienast Y, Vettel C, Loos EK, Kutschera S, Bartels S, Appak S, Besemfelder E, Terhardt D, Chavakis E, Wieland T, Klein C, Thomas M, Uemura A, Goerdt S, Augustin HG. Felcht M, et al. Among authors: besemfelder e. J Clin Invest. 2012 Jun;122(6):1991-2005. doi: 10.1172/JCI58832. Epub 2012 May 15. J Clin Invest. 2012. PMID: 22585576 Free PMC article.
Endothelial cell fitness dictates the source of regenerating liver vasculature.
Singhal M, Liu X, Inverso D, Jiang K, Dai J, He H, Bartels S, Li W, Abdul Pari AA, Gengenbacher N, Besemfelder E, Hui L, Augustin HG, Hu J. Singhal M, et al. Among authors: besemfelder e. J Exp Med. 2018 Oct 1;215(10):2497-2508. doi: 10.1084/jem.20180008. Epub 2018 Sep 7. J Exp Med. 2018. PMID: 30194265 Free PMC article.
Timed Ang2-Targeted Therapy Identifies the Angiopoietin-Tie Pathway as Key Regulator of Fatal Lymphogenous Metastasis.
Gengenbacher N, Singhal M, Mogler C, Hai L, Milde L, Pari AAA, Besemfelder E, Fricke C, Baumann D, Gehrs S, Utikal J, Felcht M, Hu J, Schlesner M, Offringa R, Chintharlapalli SR, Augustin HG. Gengenbacher N, et al. Among authors: besemfelder e. Cancer Discov. 2021 Feb;11(2):424-445. doi: 10.1158/2159-8290.CD-20-0122. Epub 2020 Oct 26. Cancer Discov. 2021. PMID: 33106316
Preclinical validation of a novel metastasis-inhibiting Tie1 function-blocking antibody.
Singhal M, Gengenbacher N, La Porta S, Gehrs S, Shi J, Kamiyama M, Bodenmiller DM, Fischl A, Schieb B, Besemfelder E, Chintharlapalli S, Augustin HG. Singhal M, et al. Among authors: besemfelder e. EMBO Mol Med. 2020 Jun 8;12(6):e11164. doi: 10.15252/emmm.201911164. Epub 2020 Apr 17. EMBO Mol Med. 2020. PMID: 32302470 Free PMC article.
Temporal multi-omics identifies LRG1 as a vascular niche instructor of metastasis.
Singhal M, Gengenbacher N, Abdul Pari AA, Kamiyama M, Hai L, Kuhn BJ, Kallenberg DM, Kulkarni SR, Camilli C, Preuß SF, Leuchs B, Mogler C, Espinet E, Besemfelder E, Heide D, Heikenwalder M, Sprick MR, Trumpp A, Krijgsveld J, Schlesner M, Hu J, Moss SE, Greenwood J, Augustin HG. Singhal M, et al. Among authors: besemfelder e. Sci Transl Med. 2021 Sep;13(609):eabe6805. doi: 10.1126/scitranslmed.abe6805. Epub 2021 Sep 1. Sci Transl Med. 2021. PMID: 34516824 Free PMC article.
Cytokine-Like 1 Is a Novel Proangiogenic Factor Secreted by and Mediating Functions of Endothelial Progenitor Cells.
Schneller D, Hofer-Warbinek R, Sturtzel C, Lipnik K, Gencelli B, Seltenhammer M, Wen M, Testori J, Bilban M, Borowski A, Windwarder M, Kapel SS, Besemfelder E, Cejka P, Habertheuer A, Schlechta B, Majdic O, Altmann F, Kocher A, Augustin HG, Luttmann W, Hofer E. Schneller D, et al. Among authors: besemfelder e. Circ Res. 2019 Jan 18;124(2):243-255. doi: 10.1161/CIRCRESAHA.118.313645. Circ Res. 2019. PMID: 30582450
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