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Evidence of native α-synuclein conformers in the human brain.
Gould N, Mor DE, Lightfoot R, Malkus K, Giasson B, Ischiropoulos H. Gould N, et al. J Biol Chem. 2014 Mar 14;289(11):7929-34. doi: 10.1074/jbc.C113.538249. Epub 2014 Jan 28. J Biol Chem. 2014. PMID: 24474688 Free PMC article.
Dopamine induces soluble α-synuclein oligomers and nigrostriatal degeneration.
Mor DE, Tsika E, Mazzulli JR, Gould NS, Kim H, Daniels MJ, Doshi S, Gupta P, Grossman JL, Tan VX, Kalb RG, Caldwell KA, Caldwell GA, Wolfe JH, Ischiropoulos H. Mor DE, et al. Nat Neurosci. 2017 Nov;20(11):1560-1568. doi: 10.1038/nn.4641. Epub 2017 Sep 18. Nat Neurosci. 2017. PMID: 28920936 Free PMC article.
Cyclized NDGA modifies dynamic α-synuclein monomers preventing aggregation and toxicity.
Daniels MJ, Nourse JB Jr, Kim H, Sainati V, Schiavina M, Murrali MG, Pan B, Ferrie JJ, Haney CM, Moons R, Gould NS, Natalello A, Grandori R, Sobott F, Petersson EJ, Rhoades E, Pierattelli R, Felli I, Uversky VN, Caldwell KA, Caldwell GA, Krol ES, Ischiropoulos H. Daniels MJ, et al. Among authors: gould ns. Sci Rep. 2019 Feb 27;9(1):2937. doi: 10.1038/s41598-019-39480-z. Sci Rep. 2019. PMID: 30814575 Free PMC article.
253 results