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Hes1 upregulation contributes to the development of FIP1L1-PDGRA-positive leukemia in blast crisis.
Uchida T, Kitaura J, Nakahara F, Togami K, Inoue D, Maehara A, Nishimura K, Kawabata KC, Doki N, Kakihana K, Yoshioka K, Izawa K, Oki T, Sada A, Harada Y, Ohashi K, Katayama Y, Matsui T, Harada H, Kitamura T. Uchida T, et al. Exp Hematol. 2014 May;42(5):369-379.e3. doi: 10.1016/j.exphem.2014.01.009. Epub 2014 Jan 31. Exp Hematol. 2014. PMID: 24486648 Free article. Clinical Trial.
Myelodysplastic syndromes are induced by histone methylation–altering ASXL1 mutations.
Inoue D, Kitaura J, Togami K, Nishimura K, Enomoto Y, Uchida T, Kagiyama Y, Kawabata KC, Nakahara F, Izawa K, Oki T, Maehara A, Isobe M, Tsuchiya A, Harada Y, Harada H, Ochiya T, Aburatani H, Kimura H, Thol F, Heuser M, Levine RL, Abdel-Wahab O, Kitamura T. Inoue D, et al. Among authors: uchida t. J Clin Invest. 2013 Nov;123(11):4627-40. doi: 10.1172/JCI70739. J Clin Invest. 2013. PMID: 24216483 Free PMC article.
Hes1 promotes blast crisis in chronic myelogenous leukemia through MMP-9 upregulation in leukemic cells.
Nakahara F, Kitaura J, Uchida T, Nishida C, Togami K, Inoue D, Matsukawa T, Kagiyama Y, Enomoto Y, Kawabata KC, Chen-Yi L, Komeno Y, Izawa K, Oki T, Nagae G, Harada Y, Harada H, Otsu M, Aburatani H, Heissig B, Hattori K, Kitamura T. Nakahara F, et al. Among authors: uchida t. Blood. 2014 Jun 19;123(25):3932-42. doi: 10.1182/blood-2013-01-476747. Epub 2014 May 13. Blood. 2014. PMID: 24825862 Free article.
[Molecular basis of hematological malignancies].
Kitamura T, Inoue D, Nakahara F, Okochi N, Kato N, Togami K, Uchida T, Kagiyama Y, Kawabata KC, Nagase R, Horikawa S, Hayashi K, Saika M, Izawa K, Oki T, Chiba S, Harada Y, Harada H, Kitaura J. Kitamura T, et al. Among authors: uchida t. Rinsho Ketsueki. 2014 Oct;55(10):1715-23. Rinsho Ketsueki. 2014. PMID: 25297732 Review. Japanese. No abstract available.
3,640 results