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Systems level profiling of chemotherapy-induced stress resolution in cancer cells reveals druggable trade-offs.
Saavedra-García P, Roman-Trufero M, Al-Sadah HA, Blighe K, López-Jiménez E, Christoforou M, Penfold L, Capece D, Xiong X, Miao Y, Parzych K, Caputo VS, Siskos AP, Encheva V, Liu Z, Thiel D, Kaiser MF, Piazza P, Chaidos A, Karadimitris A, Franzoso G, Snijders AP, Keun HC, Oyarzún DA, Barahona M, Auner HW. Saavedra-García P, et al. Among authors: snijders ap. Proc Natl Acad Sci U S A. 2021 Apr 27;118(17):e2018229118. doi: 10.1073/pnas.2018229118. Proc Natl Acad Sci U S A. 2021. PMID: 33883278 Free PMC article.
PIM1 controls GBP1 activity to limit self-damage and to guard against pathogen infection.
Fisch D, Pfleiderer MM, Anastasakou E, Mackie GM, Wendt F, Liu X, Clough B, Lara-Reyna S, Encheva V, Snijders AP, Bando H, Yamamoto M, Beggs AD, Mercer J, Shenoy AR, Wollscheid B, Maslowski KM, Galej WP, Frickel EM. Fisch D, et al. Among authors: snijders ap. Science. 2023 Oct 6;382(6666):eadg2253. doi: 10.1126/science.adg2253. Epub 2023 Oct 6. Science. 2023. PMID: 37797010 Free PMC article.
A ubiquitylation site in Cockayne syndrome B required for repair of oxidative DNA damage, but not for transcription-coupled nucleotide excision repair.
Ranes M, Boeing S, Wang Y, Wienholz F, Menoni H, Walker J, Encheva V, Chakravarty P, Mari PO, Stewart A, Giglia-Mari G, Snijders AP, Vermeulen W, Svejstrup JQ. Ranes M, et al. Among authors: snijders ap. Nucleic Acids Res. 2016 Jun 20;44(11):5246-55. doi: 10.1093/nar/gkw216. Epub 2016 Apr 7. Nucleic Acids Res. 2016. PMID: 27060134 Free PMC article.
LUBAC determines chemotherapy resistance in squamous cell lung cancer.
Ruiz EJ, Diefenbacher ME, Nelson JK, Sancho R, Pucci F, Chakraborty A, Moreno P, Annibaldi A, Liccardi G, Encheva V, Mitter R, Rosenfeldt M, Snijders AP, Meier P, Calzado MA, Behrens A. Ruiz EJ, et al. Among authors: snijders ap. J Exp Med. 2019 Feb 4;216(2):450-465. doi: 10.1084/jem.20180742. Epub 2019 Jan 14. J Exp Med. 2019. PMID: 30642944 Free PMC article.
167 results