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Cdk1 is sufficient to drive the mammalian cell cycle.
Santamaría D, Barrière C, Cerqueira A, Hunt S, Tardy C, Newton K, Cáceres JF, Dubus P, Malumbres M, Barbacid M. Santamaría D, et al. Nature. 2007 Aug 16;448(7155):811-5. doi: 10.1038/nature06046. Nature. 2007. PMID: 17700700
Mice thrive without Cdk4 and Cdk2.
Barrière C, Santamaría D, Cerqueira A, Galán J, Martín A, Ortega S, Malumbres M, Dubus P, Barbacid M. Barrière C, et al. Among authors: santamaria d. Mol Oncol. 2007 Jun;1(1):72-83. doi: 10.1016/j.molonc.2007.03.001. Epub 2007 Mar 14. Mol Oncol. 2007. PMID: 19383288 Free PMC article.
Overall Cdk activity modulates the DNA damage response in mammalian cells.
Cerqueira A, Santamaría D, Martínez-Pastor B, Cuadrado M, Fernández-Capetillo O, Barbacid M. Cerqueira A, et al. Among authors: santamaria d. J Cell Biol. 2009 Dec 14;187(6):773-80. doi: 10.1083/jcb.200903033. J Cell Biol. 2009. PMID: 19995934 Free PMC article.
Cdk6-dependent regulation of G(1) length controls adult neurogenesis.
Beukelaers P, Vandenbosch R, Caron N, Nguyen L, Belachew S, Moonen G, Kiyokawa H, Barbacid M, Santamaria D, Malgrange B. Beukelaers P, et al. Among authors: santamaria d. Stem Cells. 2011 Apr;29(4):713-24. doi: 10.1002/stem.616. Stem Cells. 2011. PMID: 21319271
69 results