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Page 1
Challenges for inhaled drug discovery and development: Induced alveolar macrophage responses.
Forbes B, O'Lone R, Allen PP, Cahn A, Clarke C, Collinge M, Dailey LA, Donnelly LE, Dybowski J, Hassall D, Hildebrand D, Jones R, Kilgour J, Klapwijk J, Maier CC, McGovern T, Nikula K, Parry JD, Reed MD, Robinson I, Tomlinson L, Wolfreys A. Forbes B, et al. Among authors: tomlinson l. Adv Drug Deliv Rev. 2014 May;71:15-33. doi: 10.1016/j.addr.2014.02.001. Epub 2014 Feb 13. Adv Drug Deliv Rev. 2014. PMID: 24530633 Free article.
Principles for Assessing Adversity in Toxicologic Clinical Pathology.
Ramaiah L, Tomlinson L, Tripathi NK, Cregar LC, Vitsky A, Beust BV, Barlow VG, Reagan WJ, Ennulat D. Ramaiah L, et al. Among authors: tomlinson l. Toxicol Pathol. 2017 Feb;45(2):260-266. doi: 10.1177/0192623316681646. Epub 2017 Jan 5. Toxicol Pathol. 2017. PMID: 28056663 Review.
Scientific and Regulatory Policy Committee Points to Consider Review: Inclusion of Reproductive and Pathology End Points for Assessment of Reproductive and Developmental Toxicity in Pharmaceutical Drug Development.
Halpern WG, Ameri M, Bowman CJ, Elwell MR, Mirsky ML, Oliver J, Regan KS, Remick AK, Sutherland VL, Thompson KE, Tremblay C, Yoshida M, Tomlinson L. Halpern WG, et al. Among authors: tomlinson l. Toxicol Pathol. 2016 Aug;44(6):789-809. doi: 10.1177/0192623316650052. Epub 2016 May 27. Toxicol Pathol. 2016. PMID: 27235322 Free PMC article.
Characterizing "Adversity" of Pathology Findings in Nonclinical Toxicity Studies: Results from the 4th ESTP International Expert Workshop.
Palazzi X, Burkhardt JE, Caplain H, Dellarco V, Fant P, Foster JR, Francke S, Germann P, Gröters S, Harada T, Harleman J, Inui K, Kaufmann W, Lenz B, Nagai H, Pohlmeyer-Esch G, Schulte A, Skydsgaard M, Tomlinson L, Wood CE, Yoshida M. Palazzi X, et al. Among authors: tomlinson l. Toxicol Pathol. 2016 Aug;44(6):810-24. doi: 10.1177/0192623316642527. Epub 2016 Apr 21. Toxicol Pathol. 2016. PMID: 27102650
Perspectives on the evaluation and adoption of complex in vitro models in drug development: Workshop with the FDA and the pharmaceutical industry (IQ MPS Affiliate).
Baran SW, Brown PC, Baudy AR, Fitzpatrick SC, Frantz C, Fullerton A, Gan J, Hardwick RN, Hillgren KM, Kopec AK, Liras JL, Mendrick DL, Nagao R, Proctor WR, Ramsden D, Ribeiro AJS, Stresser D, Sung KE, Sura R, Tetsuka K, Tomlinson L, Van Vleet T, Wagoner MP, Wang Q, Arslan SY, Yoder G, Ekert JE. Baran SW, et al. Among authors: tomlinson l. ALTEX. 2022;39(2):297–314. doi: 10.14573/altex.2112203. Epub 2022 Jan 21. ALTEX. 2022. PMID: 35064273 Free article.
Experiments in the EpiDerm 3D Skin In Vitro Model and Minipigs In Vivo Indicate Comparatively Lower In Vivo Skin Sensitivity of Topically Applied Aneugenic Compounds.
Schuler M, Tomlinson L, Homiski M, Cheung J, Zhan Y, Coffing S, Engel M, Rubitski E, Seitis G, Hales K, Robertson A, Vispute S, Cook J, Radi Z, Hollingshead B. Schuler M, et al. Among authors: tomlinson l. Toxicol Sci. 2021 Feb 26;180(1):103-121. doi: 10.1093/toxsci/kfaa189. Toxicol Sci. 2021. PMID: 33481035
Cannabinoid receptor antagonist-induced striated muscle toxicity and ethylmalonic-adipic aciduria in beagle dogs.
Tomlinson L, Tirmenstein MA, Janovitz EB, Aranibar N, Ott KH, Kozlosky JC, Patrone LM, Achanzar WE, Augustine KA, Brannen KC, Carlson KE, Charlap JH, Dubrow KM, Kang L, Rosini LT, Panzica-Kelly JM, Flint OP, Moulin FJ, Megill JR, Zhang H, Bennett MJ, Horvath JJ. Tomlinson L, et al. Toxicol Sci. 2012 Oct;129(2):268-79. doi: 10.1093/toxsci/kfs217. Epub 2012 Jul 21. Toxicol Sci. 2012. PMID: 22821849
490 results