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A phase 1 trial of oncolytic HSV-1, G207, given in combination with radiation for recurrent GBM demonstrates safety and radiographic responses.
Markert JM, Razdan SN, Kuo HC, Cantor A, Knoll A, Karrasch M, Nabors LB, Markiewicz M, Agee BS, Coleman JM, Lakeman AD, Palmer CA, Parker JN, Whitley RJ, Weichselbaum RR, Fiveash JB, Gillespie GY. Markert JM, et al. Among authors: fiveash jb. Mol Ther. 2014 May;22(5):1048-55. doi: 10.1038/mt.2014.22. Epub 2014 Feb 27. Mol Ther. 2014. PMID: 24572293 Free PMC article. Clinical Trial.
Phase I trial of erlotinib with radiation therapy in patients with glioblastoma multiforme: results of North Central Cancer Treatment Group protocol N0177.
Krishnan S, Brown PD, Ballman KV, Fiveash JB, Uhm JH, Giannini C, Jaeckle KA, Geoffroy FJ, Nabors LB, Buckner JC; North Central Cancer Treatment Group. Krishnan S, et al. Among authors: fiveash jb. Int J Radiat Oncol Biol Phys. 2006 Jul 15;65(4):1192-9. doi: 10.1016/j.ijrobp.2006.01.018. Epub 2006 Apr 19. Int J Radiat Oncol Biol Phys. 2006. PMID: 16626884 Clinical Trial.
Phase I single-dose study of intracavitary-administered iodine-131-TM-601 in adults with recurrent high-grade glioma.
Mamelak AN, Rosenfeld S, Bucholz R, Raubitschek A, Nabors LB, Fiveash JB, Shen S, Khazaeli MB, Colcher D, Liu A, Osman M, Guthrie B, Schade-Bijur S, Hablitz DM, Alvarez VL, Gonda MA. Mamelak AN, et al. Among authors: fiveash jb. J Clin Oncol. 2006 Aug 1;24(22):3644-50. doi: 10.1200/JCO.2005.05.4569. J Clin Oncol. 2006. PMID: 16877732 Clinical Trial.
136 results