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A phase 1 trial of oncolytic HSV-1, G207, given in combination with radiation for recurrent GBM demonstrates safety and radiographic responses.
Markert JM, Razdan SN, Kuo HC, Cantor A, Knoll A, Karrasch M, Nabors LB, Markiewicz M, Agee BS, Coleman JM, Lakeman AD, Palmer CA, Parker JN, Whitley RJ, Weichselbaum RR, Fiveash JB, Gillespie GY. Markert JM, et al. Among authors: karrasch m. Mol Ther. 2014 May;22(5):1048-55. doi: 10.1038/mt.2014.22. Epub 2014 Feb 27. Mol Ther. 2014. PMID: 24572293 Free PMC article. Clinical Trial.
Phase I, open-label, dose-escalating study of a genetically engineered herpes simplex virus, NV1020, in subjects with metastatic colorectal carcinoma to the liver.
Kemeny N, Brown K, Covey A, Kim T, Bhargava A, Brody L, Guilfoyle B, Haag NP, Karrasch M, Glasschroeder B, Knoll A, Getrajdman G, Kowal KJ, Jarnagin WR, Fong Y. Kemeny N, et al. Among authors: karrasch m. Hum Gene Ther. 2006 Dec;17(12):1214-24. doi: 10.1089/hum.2006.17.1214. Hum Gene Ther. 2006. PMID: 17107303 Clinical Trial.
Vaccination trial with HPV16 L1E7 chimeric virus-like particles in women suffering from high grade cervical intraepithelial neoplasia (CIN 2/3).
Kaufmann AM, Nieland JD, Jochmus I, Baur S, Friese K, Gabelsberger J, Gieseking F, Gissmann L, Glasschröder B, Grubert T, Hillemanns P, Höpfl R, Ikenberg H, Schwarz J, Karrasch M, Knoll A, Küppers V, Lechmann M, Lelle RJ, Meissner H, Müller RT, Pawlita M, Petry KU, Pilch H, Walek E, Schneider A. Kaufmann AM, et al. Among authors: karrasch m. Int J Cancer. 2007 Dec 15;121(12):2794-800. doi: 10.1002/ijc.23022. Int J Cancer. 2007. PMID: 17721997 Clinical Trial.
Primary Epstein-Barr virus infection and probable parvovirus B19 reactivation resulting in fulminant hepatitis and fulfilling five of eight criteria for hemophagocytic lymphohistiocytosis.
Karrasch M, Felber J, Keller PM, Kletta C, Egerer R, Bohnert J, Hermann B, Pfister W, Theis B, Petersen I, Stallmach A, Baier M. Karrasch M, et al. Int J Infect Dis. 2014 Nov;28:143-6. doi: 10.1016/j.ijid.2014.08.003. Epub 2014 Sep 19. Int J Infect Dis. 2014. PMID: 25242697 Free article.
102 results