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A phase 1 trial of oncolytic HSV-1, G207, given in combination with radiation for recurrent GBM demonstrates safety and radiographic responses.
Markert JM, Razdan SN, Kuo HC, Cantor A, Knoll A, Karrasch M, Nabors LB, Markiewicz M, Agee BS, Coleman JM, Lakeman AD, Palmer CA, Parker JN, Whitley RJ, Weichselbaum RR, Fiveash JB, Gillespie GY. Markert JM, et al. Among authors: lakeman ad. Mol Ther. 2014 May;22(5):1048-55. doi: 10.1038/mt.2014.22. Epub 2014 Feb 27. Mol Ther. 2014. PMID: 24572293 Free PMC article. Clinical Trial.
Detection of cytomegalovirus (CMV) DNA by polymerase chain reaction is associated with hearing loss in newborns with symptomatic congenital CMV infection involving the central nervous system.
Bradford RD, Cloud G, Lakeman AD, Boppana S, Kimberlin DW, Jacobs R, Demmler G, Sanchez P, Britt W, Soong SJ, Whitley RJ; National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. Bradford RD, et al. Among authors: lakeman ad. J Infect Dis. 2005 Jan 15;191(2):227-33. doi: 10.1086/426456. Epub 2004 Dec 16. J Infect Dis. 2005. PMID: 15609232
A rabbit model of focal herpes simplex encephalitis.
Schlitt M, Lakeman AD, Wilson ER, To A, Acoff RW, Harsh GR 3rd, Whitley RJ. Schlitt M, et al. Among authors: lakeman ad. J Infect Dis. 1986 Apr;153(4):732-5. doi: 10.1093/infdis/153.4.732. J Infect Dis. 1986. PMID: 3005433
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