APC alterations are frequently involved in the pathogenesis of acinar cell carcinoma of the pancreas, mainly through gene loss and promoter hypermethylation.
Furlan D, Sahnane N, Bernasconi B, Frattini M, Tibiletti MG, Molinari F, Marando A, Zhang L, Vanoli A, Casnedi S, Adsay V, Notohara K, Albarello L, Asioli S, Sessa F, Capella C, La Rosa S.
Furlan D, et al. Among authors: sahnane n.
Virchows Arch. 2014 May;464(5):553-64. doi: 10.1007/s00428-014-1562-1. Epub 2014 Mar 4.
Virchows Arch. 2014.
PMID: 24590585