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A lectin from Bothrops leucurus snake venom raises cytosolic calcium levels and promotes B16-F10 melanoma necrotic cell death via mitochondrial permeability transition.
Aranda-Souza MA, Rossato FA, Costa RA, Figueira TR, Castilho RF, Guarniere MC, Nunes ES, Coelho LC, Correia MT, Vercesi AE. Aranda-Souza MA, et al. Among authors: rossato fa. Toxicon. 2014 May;82:97-103. doi: 10.1016/j.toxicon.2014.02.018. Epub 2014 Mar 1. Toxicon. 2014. PMID: 24593964 Free article.
pCramoll and rCramoll lectins induce cell death in human prostate adenocarcinoma (PC-3) cells by impairment of mitochondrial homeostasis.
de Oliveira Figueirôa E, Aranda-Souza MÂ, Varejão N, Rossato FA, Costa RAP, Figueira TR, da Silva LCN, Castilho RF, Vercesi AE, Dos Santos Correia MT. de Oliveira Figueirôa E, et al. Among authors: rossato fa. Toxicol In Vitro. 2017 Sep;43:40-46. doi: 10.1016/j.tiv.2017.05.016. Epub 2017 May 25. Toxicol In Vitro. 2017. PMID: 28552641 Free article.
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