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Mutations in ANKS6 cause a nephronophthisis-like phenotype with ESRD.
Taskiran EZ, Korkmaz E, Gucer S, Kosukcu C, Kaymaz F, Koyunlar C, Bryda EC, Chaki M, Lu D, Vadnagara K, Candan C, Topaloglu R, Schaefer F, Attanasio M, Bergmann C, Ozaltin F. Taskiran EZ, et al. Among authors: lu d. J Am Soc Nephrol. 2014 Aug;25(8):1653-61. doi: 10.1681/ASN.2013060646. Epub 2014 Mar 7. J Am Soc Nephrol. 2014. PMID: 24610927 Free PMC article.
DGKE variants cause a glomerular microangiopathy that mimics membranoproliferative GN.
Ozaltin F, Li B, Rauhauser A, An SW, Soylemezoglu O, Gonul II, Taskiran EZ, Ibsirlioglu T, Korkmaz E, Bilginer Y, Duzova A, Ozen S, Topaloglu R, Besbas N, Ashraf S, Du Y, Liang C, Chen P, Lu D, Vadnagara K, Arbuckle S, Lewis D, Wakeland B, Quigg RJ, Ransom RF, Wakeland EK, Topham MK, Bazan NG, Mohan C, Hildebrandt F, Bakkaloglu A, Huang CL, Attanasio M. Ozaltin F, et al. Among authors: lu d. J Am Soc Nephrol. 2013 Feb;24(3):377-84. doi: 10.1681/ASN.2012090903. Epub 2012 Dec 28. J Am Soc Nephrol. 2013. PMID: 23274426 Free PMC article.
Loss of diacylglycerol kinase epsilon in mice causes endothelial distress and impairs glomerular Cox-2 and PGE2 production.
Zhu J, Chaki M, Lu D, Ren C, Wang SS, Rauhauser A, Li B, Zimmerman S, Jun B, Du Y, Vadnagara K, Wang H, Elhadi S, Quigg RJ, Topham MK, Mohan C, Ozaltin F, Zhou XJ, Marciano DK, Bazan NG, Attanasio M. Zhu J, et al. Among authors: lu d. Am J Physiol Renal Physiol. 2016 May 1;310(9):F895-908. doi: 10.1152/ajprenal.00431.2015. Epub 2016 Feb 17. Am J Physiol Renal Physiol. 2016. PMID: 26887830 Free PMC article.
Recently, we and others have described a genetic form of TMA caused by mutations in the gene diacylglycerol kinase-epsilon (DGKE) that encodes the lipid kinase DGKepsilon (Lemaire M, Fremeaux-Bacchi V, Schaefer F, Choi MR, Tang WH, Le Quintrec M, Fakhouri F, Taque S, Nobili F, Ma …
Recently, we and others have described a genetic form of TMA caused by mutations in the gene diacylglycerol kinase-epsilon (DGKE) that encod …
Hedgehog signaling indirectly affects tubular cell survival after obstructive kidney injury.
Rauhauser AA, Ren C, Lu D, Li B, Zhu J, McEnery K, Vadnagara K, Zepeda-Orozco D, Zhou XJ, Lin F, Jetten AM, Attanasio M. Rauhauser AA, et al. Among authors: lu d. Am J Physiol Renal Physiol. 2015 Nov 1;309(9):F770-8. doi: 10.1152/ajprenal.00232.2015. Epub 2015 Aug 19. Am J Physiol Renal Physiol. 2015. PMID: 26290370 Free PMC article.
Epithelial innate immunity mediates tubular cell senescence after kidney injury.
Jin H, Zhang Y, Ding Q, Wang SS, Rastogi P, Dai DF, Lu D, Purvis M, Cao C, Wang A, Liu D, Ren C, Elhadi S, Hu MC, Chai Y, Zepeda-Orozco D, Campisi J, Attanasio M. Jin H, et al. Among authors: lu d. JCI Insight. 2019 Jan 24;4(2):e125490. doi: 10.1172/jci.insight.125490. JCI Insight. 2019. PMID: 30674725 Free PMC article.
Prominin-1 controls stem cell activation by orchestrating ciliary dynamics.
Singer D, Thamm K, Zhuang H, Karbanová J, Gao Y, Walker JV, Jin H, Wu X, Coveney CR, Marangoni P, Lu D, Grayson PRC, Gulsen T, Liu KJ, Ardu S, Wann AK, Luo S, Zambon AC, Jetten AM, Tredwin C, Klein OD, Attanasio M, Carmeliet P, Huttner WB, Corbeil D, Hu B. Singer D, et al. Among authors: lu d. EMBO J. 2019 Jan 15;38(2):e99845. doi: 10.15252/embj.201899845. Epub 2018 Dec 6. EMBO J. 2019. PMID: 30523147 Free PMC article.
8,518 results