Tam AB - Search Results

1

ORMDL3 transgenic mice have increased airway remodeling and airway responsiveness characteristic of asthma.

Miller M, Rosenthal P, Beppu A, Mueller JL, Hoffman HM, Tam AB, Doherty TA, McGeough MD, Pena CA, Suzukawa M, Niwa M, Broide DH. Miller M, et al. Among authors: tam ab. J Immunol. 2014 Apr 15;192(8):3475-87. doi: 10.4049/jimmunol.1303047. Epub 2014 Mar 12. J Immunol. 2014. PMID: 24623133 Free PMC article.

2

ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6.

Miller M, Tam AB, Cho JY, Doherty TA, Pham A, Khorram N, Rosenthal P, Mueller JL, Hoffman HM, Suzukawa M, Niwa M, Broide DH. Miller M, et al. Among authors: tam ab. Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16648-53. doi: 10.1073/pnas.1204151109. Epub 2012 Sep 24. Proc Natl Acad Sci U S A. 2012. PMID: 23011799 Free PMC article.

3

Cutting Edge: Targeting Epithelial ORMDL3 Increases, Rather than Reduces, Airway Responsiveness and Is Associated with Increased Sphingosine-1-Phosphate.

Miller M, Tam AB, Mueller JL, Rosenthal P, Beppu A, Gordillo R, McGeough MD, Vuong C, Doherty TA, Hoffman HM, Niwa M, Broide DH. Miller M, et al. Among authors: tam ab. J Immunol. 2017 Apr 15;198(8):3017-3022. doi: 10.4049/jimmunol.1601848. Epub 2017 Mar 8. J Immunol. 2017. PMID: 28275141 Free PMC article.

4

Intrinsic capacities of molecular sensors of the unfolded protein response to sense alternate forms of endoplasmic reticulum stress.

DuRose JB, Tam AB, Niwa M. DuRose JB, et al. Among authors: tam ab. Mol Biol Cell. 2006 Jul;17(7):3095-107. doi: 10.1091/mbc.e06-01-0055. Epub 2006 May 3. Mol Biol Cell. 2006. PMID: 16672378 Free PMC article.

5

ER stress activates NF-κB by integrating functions of basal IKK activity, IRE1 and PERK.

Tam AB, Mercado EL, Hoffmann A, Niwa M. Tam AB, et al. PLoS One. 2012;7(10):e45078. doi: 10.1371/journal.pone.0045078. Epub 2012 Oct 26. PLoS One. 2012. PMID: 23110043 Free PMC article.

6

Ire1 has distinct catalytic mechanisms for XBP1/HAC1 splicing and RIDD.

Tam AB, Koong AC, Niwa M. Tam AB, et al. Cell Rep. 2014 Nov 6;9(3):850-8. doi: 10.1016/j.celrep.2014.09.016. Epub 2014 Oct 30. Cell Rep. 2014. PMID: 25437541 Free PMC article.

7

The UPR Activator ATF6 Responds to Proteotoxic and Lipotoxic Stress by Distinct Mechanisms.

Tam AB, Roberts LS, Chandra V, Rivera IG, Nomura DK, Forbes DJ, Niwa M. Tam AB, et al. Dev Cell. 2018 Aug 6;46(3):327-343.e7. doi: 10.1016/j.devcel.2018.04.023. Dev Cell. 2018. PMID: 30086303 Free PMC article.

8

Identification of Doxorubicin as an Inhibitor of the IRE1α-XBP1 Axis of the Unfolded Protein Response.

Jiang D, Lynch C, Medeiros BC, Liedtke M, Bam R, Tam AB, Yang Z, Alagappan M, Abidi P, Le QT, Giaccia AJ, Denko NC, Niwa M, Koong AC. Jiang D, et al. Among authors: tam ab. Sci Rep. 2016 Sep 16;6:33353. doi: 10.1038/srep33353. Sci Rep. 2016. PMID: 27634301 Free PMC article.

9

Acridine Derivatives as Inhibitors of the IRE1α-XBP1 Pathway Are Cytotoxic to Human Multiple Myeloma.

Jiang D, Tam AB, Alagappan M, Hay MP, Gupta A, Kozak MM, Solow-Cordero DE, Lum PY, Denko NC, Giaccia AJ, Le QT, Niwa M, Koong AC. Jiang D, et al. Among authors: tam ab. Mol Cancer Ther. 2016 Sep;15(9):2055-65. doi: 10.1158/1535-7163.MCT-15-1023. Epub 2016 Jun 15. Mol Cancer Ther. 2016. PMID: 27307600 Free PMC article.

10

Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma.

Papandreou I, Denko NC, Olson M, Van Melckebeke H, Lust S, Tam A, Solow-Cordero DE, Bouley DM, Offner F, Niwa M, Koong AC. Papandreou I, et al. Blood. 2011 Jan 27;117(4):1311-4. doi: 10.1182/blood-2010-08-303099. Epub 2010 Nov 16. Blood. 2011. PMID: 21081713 Free PMC article.

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