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Novel diversity-oriented synthesis-derived respiratory syncytial virus inhibitors identified via a high throughput replicon-based screen.
Duvall JR, VerPlank L, Ludeke B, McLeod SM, Lee MD 4th, Vishwanathan K, Mulrooney CA, Le Quement S, Yu Q, Palmer MA, Fleming P, Fearns R, Foley MA, Scherer CA. Duvall JR, et al. Among authors: verplank l. Antiviral Res. 2016 Jul;131:19-25. doi: 10.1016/j.antiviral.2016.03.015. Epub 2016 Apr 6. Antiviral Res. 2016. PMID: 27059228 Free PMC article.
APOL1 kidney disease risk variants cause cytotoxicity by depleting cellular potassium and inducing stress-activated protein kinases.
Olabisi OA, Zhang JY, VerPlank L, Zahler N, DiBartolo S 3rd, Heneghan JF, Schlöndorff JS, Suh JH, Yan P, Alper SL, Friedman DJ, Pollak MR. Olabisi OA, et al. Among authors: verplank l. Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):830-7. doi: 10.1073/pnas.1522913113. Epub 2015 Dec 23. Proc Natl Acad Sci U S A. 2016. PMID: 26699492 Free PMC article.
Identification of ML359 as a Small Molecule Inhibitor of Protein Disulfide Isomerase.
Khodier C, VerPlank L, Nag PP, Pu J, Wurst J, Pilyugina T, Dockendorff C, Galinski CN, Scalise AA, Passam F, van Hessem L, Dilks J, Kennedy DR, Flaumenhaft R, Palmer MAJ, Dandapani S, Munoz B, Schrieber SL. Khodier C, et al. Among authors: verplank l. 2013 Apr 12 [updated 2014 Sep 18]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2013 Apr 12 [updated 2014 Sep 18]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 24624466 Free Books & Documents. Review.
Identification of a Selective Small-Molecule Inhibitor of Breast Cancer Stem Cells—Probe 2.
Carmody LC, Germain A, Morgan B, VerPlank L, Fernandez C, Feng Y, Perez JR, Dandapani S, Munoz B, Palmer M, Lander ES, Gupta PB, Schreiber SL. Carmody LC, et al. Among authors: verplank l. 2011 Nov 30 [updated 2014 May 13]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2011 Nov 30 [updated 2014 May 13]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 23762951 Free Books & Documents. Review.
Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia.
Gutierrez A, Pan L, Groen RW, Baleydier F, Kentsis A, Marineau J, Grebliunaite R, Kozakewich E, Reed C, Pflumio F, Poglio S, Uzan B, Clemons P, VerPlank L, An F, Burbank J, Norton S, Tolliday N, Steen H, Weng AP, Yuan H, Bradner JE, Mitsiades C, Look AT, Aster JC. Gutierrez A, et al. Among authors: verplank l. J Clin Invest. 2014 Feb;124(2):644-55. doi: 10.1172/JCI65093. Epub 2014 Jan 9. J Clin Invest. 2014. PMID: 24401270 Free PMC article.
Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation.
Frumm SM, Fan ZP, Ross KN, Duvall JR, Gupta S, VerPlank L, Suh BC, Holson E, Wagner FF, Smith WB, Paranal RM, Bassil CF, Qi J, Roti G, Kung AL, Bradner JE, Tolliday N, Stegmaier K. Frumm SM, et al. Among authors: verplank l. Chem Biol. 2013 May 23;20(5):713-25. doi: 10.1016/j.chembiol.2013.03.020. Chem Biol. 2013. PMID: 23706636 Free PMC article.
Identification of a Selective Small-Molecule Inhibitor of Breast Cancer Stem Cells - Probe 3.
Carmody L, Germain A, Morgan B, VerPlank L, Fernandez C, Feng Y, Perez J, Dandapani S, Munoz B, Palmer M, Lander ES, Gupta PB, Schreiber SL. Carmody L, et al. Among authors: verplank l. 2011 Sep 28 [updated 2013 Mar 7]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2011 Sep 28 [updated 2013 Mar 7]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 23762939 Free Books & Documents. Review.
24 results