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The circadian clock regulates rhythmic activation of the NRF2/glutathione-mediated antioxidant defense pathway to modulate pulmonary fibrosis.
Pekovic-Vaughan V, Gibbs J, Yoshitane H, Yang N, Pathiranage D, Guo B, Sagami A, Taguchi K, Bechtold D, Loudon A, Yamamoto M, Chan J, van der Horst GT, Fukada Y, Meng QJ. Pekovic-Vaughan V, et al. Among authors: meng qj. Genes Dev. 2014 Mar 15;28(6):548-60. doi: 10.1101/gad.237081.113. Genes Dev. 2014. PMID: 24637114 Free PMC article.
Setting clock speed in mammals: the CK1 epsilon tau mutation in mice accelerates circadian pacemakers by selectively destabilizing PERIOD proteins.
Meng QJ, Logunova L, Maywood ES, Gallego M, Lebiecki J, Brown TM, Sládek M, Semikhodskii AS, Glossop NRJ, Piggins HD, Chesham JE, Bechtold DA, Yoo SH, Takahashi JS, Virshup DM, Boot-Handford RP, Hastings MH, Loudon ASI. Meng QJ, et al. Neuron. 2008 Apr 10;58(1):78-88. doi: 10.1016/j.neuron.2008.01.019. Neuron. 2008. PMID: 18400165 Free PMC article.
Selective inhibition of casein kinase 1 epsilon minimally alters circadian clock period.
Walton KM, Fisher K, Rubitski D, Marconi M, Meng QJ, Sládek M, Adams J, Bass M, Chandrasekaran R, Butler T, Griffor M, Rajamohan F, Serpa M, Chen Y, Claffey M, Hastings M, Loudon A, Maywood E, Ohren J, Doran A, Wager TT. Walton KM, et al. Among authors: meng qj. J Pharmacol Exp Ther. 2009 Aug;330(2):430-9. doi: 10.1124/jpet.109.151415. Epub 2009 May 19. J Pharmacol Exp Ther. 2009. PMID: 19458106
A circadian clock is not required in an arctic mammal.
Lu W, Meng QJ, Tyler NJ, Stokkan KA, Loudon AS. Lu W, et al. Among authors: meng qj. Curr Biol. 2010 Mar 23;20(6):533-7. doi: 10.1016/j.cub.2010.01.042. Epub 2010 Mar 11. Curr Biol. 2010. PMID: 20226667 Free article.
Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes.
Meng QJ, Maywood ES, Bechtold DA, Lu WQ, Li J, Gibbs JE, Dupré SM, Chesham JE, Rajamohan F, Knafels J, Sneed B, Zawadzke LE, Ohren JF, Walton KM, Wager TT, Hastings MH, Loudon AS. Meng QJ, et al. Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15240-5. doi: 10.1073/pnas.1005101107. Epub 2010 Aug 9. Proc Natl Acad Sci U S A. 2010. PMID: 20696890 Free PMC article.
121 results