Traynor JR - Search Results

1

Development of a bioavailable μ opioid receptor (MOPr) agonist, δ opioid receptor (DOPr) antagonist peptide that evokes antinociception without development of acute tolerance.

Mosberg HI, Yeomans L, Anand JP, Porter V, Sobczyk-Kojiro K, Traynor JR, Jutkiewicz EM. Mosberg HI, et al. Among authors: traynor jr. J Med Chem. 2014 Apr 10;57(7):3148-53. doi: 10.1021/jm5002088. Epub 2014 Mar 26. J Med Chem. 2014. PMID: 24641190 Free PMC article.

2

Synthesis and biological evaluation of 14-alkoxymorphinans. 11. 3-Hydroxycyprodime and analogues: opioid antagonist profile in comparison to cyprodime.

Schmidhammer H, Jennewein HK, Krassnig R, Traynor JR, Patel D, Bell K, Froschauer G, Mattersberger K, Jachs-Ewinger C, Jura P, et al. Schmidhammer H, et al. Among authors: traynor jr. J Med Chem. 1995 Aug 4;38(16):3071-7. doi: 10.1021/jm00016a010. J Med Chem. 1995. PMID: 7636870

3

Differentiation of kappa opioid agonist-induced antinociception by naltrexone apparent pA2 analysis in rhesus monkeys.

Ko MC, Butelman ER, Traynor JR, Woods JH. Ko MC, et al. Among authors: traynor jr. J Pharmacol Exp Ther. 1998 May;285(2):518-26. J Pharmacol Exp Ther. 1998. PMID: 9580592 Free PMC article.

4

3-Alkyl ethers of clocinnamox: delayed long-term mu-antagonists with variable mu efficacy.

Husbands SM, Sadd J, Broadbear JH, Woods JH, Martin J, Traynor JR, Aceto MD, Bowman ER, Harris LS, Lewis JW. Husbands SM, et al. Among authors: traynor jr. J Med Chem. 1998 Aug 27;41(18):3493-8. doi: 10.1021/jm9810248. J Med Chem. 1998. PMID: 9719602

5

Design of a high affinity peptidomimetic opioid agonist from peptide pharmacophore models.

Wang C, McFadyen IJ, Traynor JR, Mosberg HI. Wang C, et al. Among authors: traynor jr. Bioorg Med Chem Lett. 1998 Oct 6;8(19):2685-8. doi: 10.1016/s0960-894x(98)00472-7. Bioorg Med Chem Lett. 1998. PMID: 9873603

6

The effects of the phyllolitorin analogue [desTrp(3), Leu(8)]phyllolitorin on scratching induced by bombesin and related peptides in rats.

Johnson MD, Ko M, Choo KS, Traynor JR, Mosberg HI, Naughton NN, Woods JH. Johnson MD, et al. Among authors: traynor jr. Brain Res. 1999 Aug 21;839(1):194-8. doi: 10.1016/s0006-8993(99)01708-4. Brain Res. 1999. PMID: 10482814 Free PMC article.

7

Constitutive activity of the delta-opioid receptor expressed in C6 glioma cells: identification of non-peptide delta-inverse agonists.

Neilan CL, Akil H, Woods JH, Traynor JR. Neilan CL, et al. Among authors: traynor jr. Br J Pharmacol. 1999 Oct;128(3):556-62. doi: 10.1038/sj.bjp.0702816. Br J Pharmacol. 1999. PMID: 10516632 Free PMC article.

8

Modifications of the cyclic mu receptor selective tetrapeptide Tyr-c[D-Cys-Phe-D-Pen]NH2 (Et): effects on opioid receptor binding and activation.

McFadyen IJ, Ho JC, Mosberg HI, Traynor JR. McFadyen IJ, et al. Among authors: traynor jr. J Pept Res. 2000 Mar;55(3):255-61. doi: 10.1034/j.1399-3011.2000.00177.x. J Pept Res. 2000. PMID: 10727108 Free article.

9

Antinociceptive and other behavioral effects of the steroid SC17599 are mediated by the mu-opioid receptor.

Houshyar H, Mc Fadyen IJ, Woods JH, Traynor JR. Houshyar H, et al. Among authors: traynor jr. Eur J Pharmacol. 2000 Apr 28;395(2):121-8. doi: 10.1016/s0014-2999(00)00176-x. Eur J Pharmacol. 2000. PMID: 10794817

10

Methocinnamox is a potent, long-lasting, and selective antagonist of morphine-mediated antinociception in the mouse: comparison with clocinnamox, beta-funaltrexamine, and beta-chlornaltrexamine.

Broadbear JH, Sumpter TL, Burke TF, Husbands SM, Lewis JW, Woods JH, Traynor JR. Broadbear JH, et al. Among authors: traynor jr. J Pharmacol Exp Ther. 2000 Sep;294(3):933-40. J Pharmacol Exp Ther. 2000. PMID: 10945843

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