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Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle.
Kang JE, Lim MM, Bateman RJ, Lee JJ, Smyth LP, Cirrito JR, Fujiki N, Nishino S, Holtzman DM. Kang JE, et al. Among authors: bateman rj. Science. 2009 Nov 13;326(5955):1005-7. doi: 10.1126/science.1180962. Epub 2009 Sep 24. Science. 2009. PMID: 19779148 Free PMC article.
Decreased clearance of CNS beta-amyloid in Alzheimer's disease.
Mawuenyega KG, Sigurdson W, Ovod V, Munsell L, Kasten T, Morris JC, Yarasheski KE, Bateman RJ. Mawuenyega KG, et al. Among authors: bateman rj. Science. 2010 Dec 24;330(6012):1774. doi: 10.1126/science.1197623. Epub 2010 Dec 9. Science. 2010. PMID: 21148344 Free PMC article.
Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.
Castellano JM, Kim J, Stewart FR, Jiang H, DeMattos RB, Patterson BW, Fagan AM, Morris JC, Mawuenyega KG, Cruchaga C, Goate AM, Bales KR, Paul SM, Bateman RJ, Holtzman DM. Castellano JM, et al. Among authors: bateman rj. Sci Transl Med. 2011 Jun 29;3(89):89ra57. doi: 10.1126/scitranslmed.3002156. Sci Transl Med. 2011. PMID: 21715678 Free PMC article.
Amyloid-β(1-15/16) as a marker for γ-secretase inhibition in Alzheimer's disease.
Portelius E, Zetterberg H, Dean RA, Marcil A, Bourgeois P, Nutu M, Andreasson U, Siemers E, Mawuenyega KG, Sigurdson WC, May PC, Paul SM, Holtzman DM, Blennow K, Bateman RJ. Portelius E, et al. Among authors: bateman rj. J Alzheimers Dis. 2012;31(2):335-41. doi: 10.3233/JAD-2012-120508. J Alzheimers Dis. 2012. PMID: 22531418 Free PMC article. Clinical Trial.
351 results