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Hypomethylation of the CTCFL/BORIS promoter and aberrant expression during endometrial cancer progression suggests a role as an Epi-driver gene.
Hoivik EA, Kusonmano K, Halle MK, Berg A, Wik E, Werner HM, Petersen K, Oyan AM, Kalland KH, Krakstad C, Trovik J, Widschwendter M, Salvesen HB. Hoivik EA, et al. Among authors: widschwendter m. Oncotarget. 2014 Feb 28;5(4):1052-61. doi: 10.18632/oncotarget.1697. Oncotarget. 2014. PMID: 24658009 Free PMC article.
Role of DNA methylation and epigenetic silencing of HAND2 in endometrial cancer development.
Jones A, Teschendorff AE, Li Q, Hayward JD, Kannan A, Mould T, West J, Zikan M, Cibula D, Fiegl H, Lee SH, Wik E, Hadwin R, Arora R, Lemech C, Turunen H, Pakarinen P, Jacobs IJ, Salvesen HB, Bagchi MK, Bagchi IC, Widschwendter M. Jones A, et al. Among authors: widschwendter m. PLoS Med. 2013 Nov;10(11):e1001551. doi: 10.1371/journal.pmed.1001551. Epub 2013 Nov 12. PLoS Med. 2013. PMID: 24265601 Free PMC article.
HOTAIR and its surrogate DNA methylation signature indicate carboplatin resistance in ovarian cancer.
Teschendorff AE, Lee SH, Jones A, Fiegl H, Kalwa M, Wagner W, Chindera K, Evans I, Dubeau L, Orjalo A, Horlings HM, Niederreiter L, Kaser A, Yang W, Goode EL, Fridley BL, Jenner RG, Berns EM, Wik E, Salvesen HB, Wisman GB, van der Zee AG, Davidson B, Trope CG, Lambrechts S, Vergote I, Calvert H, Jacobs IJ, Widschwendter M. Teschendorff AE, et al. Among authors: widschwendter m. Genome Med. 2015 Oct 24;7:108. doi: 10.1186/s13073-015-0233-4. Genome Med. 2015. PMID: 26497652 Free PMC article.
DNA methylation in serum and tumors of cervical cancer patients.
Widschwendter A, Müller HM, Fiegl H, Ivarsson L, Wiedemair A, Müller-Holzner E, Goebel G, Marth C, Widschwendter M. Widschwendter A, et al. Among authors: widschwendter m. Clin Cancer Res. 2004 Jan 15;10(2):565-71. doi: 10.1158/1078-0432.ccr-0825-03. Clin Cancer Res. 2004. PMID: 14760078
228 results