Wang X - Search Results

1

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy.

Mancias JD, Wang X, Gygi SP, Harper JW, Kimmelman AC. Mancias JD, et al. Among authors: wang x. Nature. 2014 May 1;509(7498):105-9. doi: 10.1038/nature13148. Epub 2014 Mar 30. Nature. 2014. PMID: 24695223 Free PMC article.

2

Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis.

Mancias JD, Pontano Vaites L, Nissim S, Biancur DE, Kim AJ, Wang X, Liu Y, Goessling W, Kimmelman AC, Harper JW. Mancias JD, et al. Among authors: wang x. Elife. 2015 Oct 5;4:e10308. doi: 10.7554/eLife.10308. Elife. 2015. PMID: 26436293 Free PMC article.

3

Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism.

Biancur DE, Paulo JA, Małachowska B, Quiles Del Rey M, Sousa CM, Wang X, Sohn ASW, Chu GC, Gygi SP, Harper JW, Fendler W, Mancias JD, Kimmelman AC. Biancur DE, et al. Among authors: wang x. Nat Commun. 2017 Jul 3;8:15965. doi: 10.1038/ncomms15965. Nat Commun. 2017. PMID: 28671190 Free PMC article.

4

Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer.

Nissim S, Leshchiner I, Mancias JD, Greenblatt MB, Maertens O, Cassa CA, Rosenfeld JA, Cox AG, Hedgepeth J, Wucherpfennig JI, Kim AJ, Henderson JE, Gonyo P, Brandt A, Lorimer E, Unger B, Prokop JW, Heidel JR, Wang XX, Ukaegbu CI, Jennings BC, Paulo JA, Gableske S, Fierke CA, Getz G, Sunyaev SR, Wade Harper J, Cichowski K, Kimmelman AC, Houvras Y, Syngal S, Williams C, Goessling W. Nissim S, et al. Nat Genet. 2019 Sep;51(9):1308-1314. doi: 10.1038/s41588-019-0475-y. Epub 2019 Aug 12. Nat Genet. 2019. PMID: 31406347 Free PMC article.

5

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway.

Son J, Lyssiotis CA, Ying H, Wang X, Hua S, Ligorio M, Perera RM, Ferrone CR, Mullarky E, Shyh-Chang N, Kang Y, Fleming JB, Bardeesy N, Asara JM, Haigis MC, DePinho RA, Cantley LC, Kimmelman AC. Son J, et al. Among authors: wang x. Nature. 2013 Apr 4;496(7443):101-5. doi: 10.1038/nature12040. Epub 2013 Mar 27. Nature. 2013. PMID: 23535601 Free PMC article.

6

Oncogenic KRAS supports pancreatic cancer through regulation of nucleotide synthesis.

Santana-Codina N, Roeth AA, Zhang Y, Yang A, Mashadova O, Asara JM, Wang X, Bronson RT, Lyssiotis CA, Ying H, Kimmelman AC. Santana-Codina N, et al. Among authors: wang x. Nat Commun. 2018 Nov 23;9(1):4945. doi: 10.1038/s41467-018-07472-8. Nat Commun. 2018. PMID: 30470748 Free PMC article.

7

Pancreatic cancers require autophagy for tumor growth.

Yang S, Wang X, Contino G, Liesa M, Sahin E, Ying H, Bause A, Li Y, Stommel JM, Dell'antonio G, Mautner J, Tonon G, Haigis M, Shirihai OS, Doglioni C, Bardeesy N, Kimmelman AC. Yang S, et al. Among authors: wang x. Genes Dev. 2011 Apr 1;25(7):717-29. doi: 10.1101/gad.2016111. Epub 2011 Mar 15. Genes Dev. 2011. PMID: 21406549 Free PMC article.

8

Inhibition of non-homologous end joining repair impairs pancreatic cancer growth and enhances radiation response.

Li YH, Wang X, Pan Y, Lee DH, Chowdhury D, Kimmelman AC. Li YH, et al. Among authors: wang x. PLoS One. 2012;7(6):e39588. doi: 10.1371/journal.pone.0039588. Epub 2012 Jun 18. PLoS One. 2012. PMID: 22724027 Free PMC article.

9

Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations.

Yang A, Rajeshkumar NV, Wang X, Yabuuchi S, Alexander BM, Chu GC, Von Hoff DD, Maitra A, Kimmelman AC. Yang A, et al. Among authors: wang x. Cancer Discov. 2014 Aug;4(8):905-13. doi: 10.1158/2159-8290.CD-14-0362. Epub 2014 May 29. Cancer Discov. 2014. PMID: 24875860 Free PMC article.

10

Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms.

Yang A, Herter-Sprie G, Zhang H, Lin EY, Biancur D, Wang X, Deng J, Hai J, Yang S, Wong KK, Kimmelman AC. Yang A, et al. Among authors: wang x. Cancer Discov. 2018 Mar;8(3):276-287. doi: 10.1158/2159-8290.CD-17-0952. Epub 2018 Jan 9. Cancer Discov. 2018. PMID: 29317452 Free PMC article.

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