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Human amyotrophic lateral sclerosis excitability phenotype screen: Target discovery and validation.
Huang X, Roet KCD, Zhang L, Brault A, Berg AP, Jefferson AB, Klug-McLeod J, Leach KL, Vincent F, Yang H, Coyle AJ, Jones LH, Frost D, Wiskow O, Chen K, Maeda R, Grantham A, Dornon MK, Klim JR, Siekmann MT, Zhao D, Lee S, Eggan K, Woolf CJ. Huang X, et al. Among authors: wiskow o. Cell Rep. 2021 Jun 8;35(10):109224. doi: 10.1016/j.celrep.2021.109224. Cell Rep. 2021. PMID: 34107252 Free PMC article.
Downregulation of the silent potassium channel Kv8.1 increases motor neuron vulnerability in amyotrophic lateral sclerosis.
Huang X, Lee S, Chen K, Kawaguchi R, Wiskow O, Ghosh S, Frost D, Perrault L, Pandey R, Klim JR, Boivin B, Hermawan C, Livak KJ, Geschwind DH, Wainger BJ, Eggan KC, Bean BP, Woolf CJ. Huang X, et al. Among authors: wiskow o. Brain Commun. 2024 Jun 11;6(3):fcae202. doi: 10.1093/braincomms/fcae202. eCollection 2024. Brain Commun. 2024. PMID: 38911266 Free PMC article.