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IGH@ translocations are prevalent in teenagers and young adults with acute lymphoblastic leukemia and are associated with a poor outcome.
Russell LJ, Enshaei A, Jones L, Erhorn A, Masic D, Bentley H, Laczko KS, Fielding AK, Goldstone AH, Goulden N, Mitchell CD, Wade R, Vora A, Moorman AV, Harrison CJ. Russell LJ, et al. Among authors: mitchell cd. J Clin Oncol. 2014 May 10;32(14):1453-62. doi: 10.1200/JCO.2013.51.3242. Epub 2014 Apr 7. J Clin Oncol. 2014. PMID: 24711557
Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: results from the UK Medical Research Council ALL97/99 randomised trial.
Moorman AV, Ensor HM, Richards SM, Chilton L, Schwab C, Kinsey SE, Vora A, Mitchell CD, Harrison CJ. Moorman AV, et al. Among authors: mitchell cd. Lancet Oncol. 2010 May;11(5):429-38. doi: 10.1016/S1470-2045(10)70066-8. Epub 2010 Apr 19. Lancet Oncol. 2010. PMID: 20409752 Clinical Trial.
Prognosis of children with acute lymphoblastic leukemia (ALL) and intrachromosomal amplification of chromosome 21 (iAMP21).
Moorman AV, Richards SM, Robinson HM, Strefford JC, Gibson BE, Kinsey SE, Eden TO, Vora AJ, Mitchell CD, Harrison CJ; UK Medical Research Council (MRC)/National Cancer Research Institute (NCRI) Childhood Leukaemia Working Party (CLWP). Moorman AV, et al. Among authors: mitchell cd. Blood. 2007 Mar 15;109(6):2327-30. doi: 10.1182/blood-2006-08-040436. Epub 2006 Nov 9. Blood. 2007. PMID: 17095619 Free article.
Demographic, clinical, and outcome features of children with acute lymphoblastic leukemia and CRLF2 deregulation: results from the MRC ALL97 clinical trial.
Ensor HM, Schwab C, Russell LJ, Richards SM, Morrison H, Masic D, Jones L, Kinsey SE, Vora AJ, Mitchell CD, Harrison CJ, Moorman AV. Ensor HM, et al. Among authors: mitchell cd. Blood. 2011 Feb 17;117(7):2129-36. doi: 10.1182/blood-2010-07-297135. Epub 2010 Nov 24. Blood. 2011. PMID: 21106984 Free article. Clinical Trial.
Risk-directed treatment intensification significantly reduces the risk of relapse among children and adolescents with acute lymphoblastic leukemia and intrachromosomal amplification of chromosome 21: a comparison of the MRC ALL97/99 and UKALL2003 trials.
Moorman AV, Robinson H, Schwab C, Richards SM, Hancock J, Mitchell CD, Goulden N, Vora A, Harrison CJ. Moorman AV, et al. Among authors: mitchell cd. J Clin Oncol. 2013 Sep 20;31(27):3389-96. doi: 10.1200/JCO.2013.48.9377. Epub 2013 Aug 12. J Clin Oncol. 2013. PMID: 23940220
Augmented post-remission therapy for a minimal residual disease-defined high-risk subgroup of children and young people with clinical standard-risk and intermediate-risk acute lymphoblastic leukaemia (UKALL 2003): a randomised controlled trial.
Vora A, Goulden N, Mitchell C, Hancock J, Hough R, Rowntree C, Moorman AV, Wade R. Vora A, et al. Lancet Oncol. 2014 Jul;15(8):809-18. doi: 10.1016/S1470-2045(14)70243-8. Epub 2014 Jun 9. Lancet Oncol. 2014. PMID: 24924991 Clinical Trial.
200 results