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Mapping the cellular response to small molecules using chemogenomic fitness signatures.
Lee AY, St Onge RP, Proctor MJ, Wallace IM, Nile AH, Spagnuolo PA, Jitkova Y, Gronda M, Wu Y, Kim MK, Cheung-Ong K, Torres NP, Spear ED, Han MK, Schlecht U, Suresh S, Duby G, Heisler LE, Surendra A, Fung E, Urbanus ML, Gebbia M, Lissina E, Miranda M, Chiang JH, Aparicio AM, Zeghouf M, Davis RW, Cherfils J, Boutry M, Kaiser CA, Cummins CL, Trimble WS, Brown GW, Schimmer AD, Bankaitis VA, Nislow C, Bader GD, Giaever G. Lee AY, et al. Among authors: zeghouf m. Science. 2014 Apr 11;344(6180):208-11. doi: 10.1126/science.1250217. Science. 2014. PMID: 24723613 Free PMC article.
Chronicles of the GTPase switch.
Cherfils J, Zeghouf M. Cherfils J, et al. Among authors: zeghouf m. Nat Chem Biol. 2011 Jul 18;7(8):493-5. doi: 10.1038/nchembio.608. Nat Chem Biol. 2011. PMID: 21769091 No abstract available.
Regulation of small GTPases by GEFs, GAPs, and GDIs.
Cherfils J, Zeghouf M. Cherfils J, et al. Among authors: zeghouf m. Physiol Rev. 2013 Jan;93(1):269-309. doi: 10.1152/physrev.00003.2012. Physiol Rev. 2013. PMID: 23303910 Free article. Review.
PH-domain-binding inhibitors of nucleotide exchange factor BRAG2 disrupt Arf GTPase signaling.
Nawrotek A, Benabdi S, Niyomchon S, Kryszke MH, Ginestier C, Cañeque T, Tepshi L, Mariani A, St Onge RP, Giaever G, Nislow C, Charafe-Jauffret E, Rodriguez R, Zeghouf M, Cherfils J. Nawrotek A, et al. Among authors: zeghouf m. Nat Chem Biol. 2019 Apr;15(4):358-366. doi: 10.1038/s41589-019-0228-3. Epub 2019 Feb 11. Nat Chem Biol. 2019. PMID: 30742123
39 results