Timm KN - Search Results

1

Detection of transgene expression using hyperpolarized 13C urea and diffusion-weighted magnetic resonance spectroscopy.

Patrick PS, Kettunen MI, Tee SS, Rodrigues TB, Serrao E, Timm KN, McGuire S, Brindle KM. Patrick PS, et al. Among authors: timm kn. Magn Reson Med. 2015 Apr;73(4):1401-6. doi: 10.1002/mrm.25254. Epub 2014 Apr 14. Magn Reson Med. 2015. PMID: 24733406 Free article.

2

(13) C magnetic resonance spectroscopic imaging of hyperpolarized [1-(13) C, U-(2) H5 ] ethanol oxidation can be used to assess aldehyde dehydrogenase activity in vivo.

Dzien P, Kettunen MI, Marco-Rius I, Serrao EM, Rodrigues TB, Larkin TJ, Timm KN, Brindle KM. Dzien P, et al. Among authors: timm kn. Magn Reson Med. 2015 May;73(5):1733-40. doi: 10.1002/mrm.25286. Epub 2014 May 6. Magn Reson Med. 2015. PMID: 24800934 Free article.

3

Hyperpolarized [U-(2) H, U-(13) C]Glucose reports on glycolytic and pentose phosphate pathway activity in EL4 tumors and glycolytic activity in yeast cells.

Timm KN, Hartl J, Keller MA, Hu DE, Kettunen MI, Rodrigues TB, Ralser M, Brindle KM. Timm KN, et al. Magn Reson Med. 2015 Dec;74(6):1543-7. doi: 10.1002/mrm.25561. Epub 2014 Dec 17. Magn Reson Med. 2015. PMID: 25522215 Free article.

4

(13) C magnetic resonance spectroscopy measurements with hyperpolarized [1-(13) C] pyruvate can be used to detect the expression of transgenic pyruvate decarboxylase activity in vivo.

Dzien P, Tee SS, Kettunen MI, Lyons SK, Larkin TJ, Timm KN, Hu DE, Wright A, Rodrigues TB, Serrao EM, Marco-Rius I, Mannion E, D'Santos P, Kennedy BW, Brindle KM. Dzien P, et al. Among authors: timm kn. Magn Reson Med. 2016 Aug;76(2):391-401. doi: 10.1002/mrm.25879. Epub 2015 Sep 21. Magn Reson Med. 2016. PMID: 26388418 Free PMC article.

5

Assessing Oxidative Stress in Tumors by Measuring the Rate of Hyperpolarized [1-13C]Dehydroascorbic Acid Reduction Using 13C Magnetic Resonance Spectroscopy.

Timm KN, Hu DE, Williams M, Wright AJ, Kettunen MI, Kennedy BWC, Larkin TJ, Dzien P, Marco-Rius I, Bohndiek SE, Brindle KM. Timm KN, et al. J Biol Chem. 2017 Feb 3;292(5):1737-1748. doi: 10.1074/jbc.M116.761536. Epub 2016 Dec 19. J Biol Chem. 2017. PMID: 27994059 Free PMC article.

6

Hyperpolarized singlet lifetimes of pyruvate in human blood and in the mouse.

Marco-Rius I, Tayler MC, Kettunen MI, Larkin TJ, Timm KN, Serrao EM, Rodrigues TB, Pileio G, Ardenkjaer-Larsen JH, Levitt MH, Brindle KM. Marco-Rius I, et al. Among authors: timm kn. NMR Biomed. 2013 Dec;26(12):1696-704. doi: 10.1002/nbm.3005. Epub 2013 Aug 15. NMR Biomed. 2013. PMID: 23946252 Free PMC article.

7

Probing hepatic metabolism of [2-¹³C]dihydroxyacetone in vivo with ¹H-decoupled hyperpolarized ¹³C-MR.

Marco-Rius I, Wright AJ, Hu DE, Savic D, Miller JJ, Timm KN, Tyler D, Brindle KM, Comment A. Marco-Rius I, et al. Among authors: timm kn. MAGMA. 2021 Feb;34(1):49-56. doi: 10.1007/s10334-020-00884-y. Epub 2020 Sep 10. MAGMA. 2021. PMID: 32910316 Free PMC article.

8

Imaging Tumor Metabolism to Assess Disease Progression and Treatment Response.

Timm KN, Kennedy BW, Brindle KM. Timm KN, et al. Clin Cancer Res. 2016 Nov 1;22(21):5196-5203. doi: 10.1158/1078-0432.CCR-16-0159. Epub 2016 Sep 8. Clin Cancer Res. 2016. PMID: 27609841 Free PMC article. Review.

9

Cardiac applications of hyperpolarised magnetic resonance.

Timm KN, Miller JJ, Henry JA, Tyler DJ. Timm KN, et al. Prog Nucl Magn Reson Spectrosc. 2018 Jun-Aug;106-107:66-87. doi: 10.1016/j.pnmrs.2018.05.002. Epub 2018 May 31. Prog Nucl Magn Reson Spectrosc. 2018. PMID: 31047602 Review.

10

Rapid,

B_{1}

-insensitive, dual-band quasi-adiabatic saturation transfer with optimal control for complete quantification of myocardial ATP flux.

Miller JJ, Valkovič L, Kerr M, Timm KN, Watson WD, Lau JYC, Tyler A, Rodgers C, Bottomley PA, Heather LC, Tyler DJ. Miller JJ, et al. Among authors: timm kn. Magn Reson Med. 2021 Jun;85(6):2978-2991. doi: 10.1002/mrm.28647. Epub 2021 Feb 3. Magn Reson Med. 2021. PMID: 33538063 Free PMC article.

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